933554
NanoFabTx™ NTA Lipid Mix
for synthesis of NTA-functionalized liposomes for small molecule delivery
Synonyme(s) :
Cholesterol, DGS-NTA(Ni), HSPC, PEG-DSPE
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About This Item
Produits recommandés
Niveau de qualité
Température de stockage
−20°C
Application
NanoFabTx™ NTA Lipid Mix is a ready-to-use nanoformulation lipid mixture for the synthesis of NTA-functionalized liposomes. This lipid mix enables users to encapsulate a wide variety of small molecules for targeting and immunotherapy applications without the need for lengthy trial-and-error optimization.
This product includes a curated lyophilized lipid mixture containing rationally selected lipids in precise ratios that have been optimized to achieve a desired size range of liposomes. Step-by-step protocols for the synthesis of liposomes surface-functionalized with NTA groups using extrusion and microfluidics are also included. The synthesized NTA-functionalized liposomes enable the conjugation of His-tagged antibodies or proteins to the liposomes surface for immunothereapy applications and multi-targeting or multi-type cargo delivery.
This product includes a curated lyophilized lipid mixture containing rationally selected lipids in precise ratios that have been optimized to achieve a desired size range of liposomes. Step-by-step protocols for the synthesis of liposomes surface-functionalized with NTA groups using extrusion and microfluidics are also included. The synthesized NTA-functionalized liposomes enable the conjugation of His-tagged antibodies or proteins to the liposomes surface for immunothereapy applications and multi-targeting or multi-type cargo delivery.
Caractéristiques et avantages
- A ready-to-use nanoformulation lipid blend for the synthesis of NTA-functionalized liposomes
- Step-by-step extrusion and microfluidics protocols for liposome synthesis developed and tested by our formulation scientists
- Flexible synthesis methods to create uniform and reproducible liposomes
- Protocols and lipid blend optimized to make liposomes around 100 nm diameter with low polydispersity
- Lipid mix optimized for His-tagged protein or antibody conjugation and small molecule encapsulation
- A lipid film hydration and extrusion protocol
- A microfluidics protocol using commercial platforms or syringe pumps
Informations légales
NANOFABTX is a trademark of Sigma-Aldrich Co. LLC
TMAX is a trademark of Merck KGaA, Darmstadt, Germany
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
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Mesoscale active matter in fluids
Soft Matter (2019)
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