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Merck
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Key Documents

921823

Sigma-Aldrich

3D-Serpentine Mixer

Fluidic 1079, PC

Synonyme(s) :

Microfluidic chip

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Description

Microfludic chip x1

Application

Microfluidic generation of droplets can produce highly monodispersed droplets with high frequency (up to hundreds of kHz). Interest in droplet-based microfluidic systems has grown substantially, because microfluidics offers the ability to handle very small volumes (μl to fl) of fluids, provides better mixing, encapsulation, sorting, and sensing. Microfluidics can be used for high throughput experimentation. Microfluidic-based droplets have many applications, including micro and nanoparticle synthesis and chemical analysis. Highly controlled droplet production also makes single cell analysis, or drug testing possible.

3D-Serpentine Mixer, Fluidic 1079, PC is made of PC (polycarbonate). The 3D serpentine mixer chip Fluidic 1079 has four identical micromixing units, which can be used for mixing very small amounts of up to three liquids. Each unit features three inlet ports and one outlet port. The mixing channel is characterized by a sequence of directional changes in all three dimensions. As there are multiple mixing structures on each chip, these can be daisy-chained to improve the mixing result.

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Microfluidic-assisted fabrication of carriers for controlled drug delivery.
Santos H A, et al.
Lab on a chip, 17, 1856-1883 (2017)
Sharma T Sanjay et al.
Advanced drug delivery reviews, 128, 3-28 (2017-09-19)
Conventional systematically-administered drugs distribute evenly throughout the body, get degraded and excreted rapidly while crossing many biological barriers, leaving minimum amounts of the drugs at pathological sites. Controlled drug delivery aims to deliver drugs to the target sites at desired
Dongfei Liu et al.
Lab on a chip, 17(11), 1856-1883 (2017-05-10)
The microfluidic technique has brought unique opportunities toward the full control over the production processes for drug delivery carriers, owing to the miniaturisation of the fluidic environment. In comparison to the conventional batch methods, the microfluidic setup provides a range

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