694037

Cesium pivalate

98%

• Synonyme(s) : Cesium 2,2-dimethylpropanoate, Cesium trimethylacetate
• Formule empirique (notation de Hill): C₅H₉O₂Cs
• Numéro CAS: 20442-70-0
• Poids moléculaire : 234.03
• Numéro MDL: MFCD10567040
• Code UNSPSC : 12352302
• ID de substance PubChem : 329761643
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: 98%
• Forme: powder
• Pf: 344-348 °C
• Chaîne SMILES: [Cs+].CC(C)(C)C([O-])=O
• InChI: 1S/C5H10O2.Cs/c1-5(2,3)4(6)7;/h1-3H3,(H,6,7);/q;+1/p-1
• Clé InChI: LGVUAXNPXVXCCW-UHFFFAOYSA-M

Description

Description générale

Cesium pivalate is an organic base widely used in palladium-catalyzed cross-coupling and carbonylation reactions due to its solubility in organic solvents.

Application

Cesium pivalate can be used as a base to synthesize:

• Fluoren-9-one derivatives by cyclocarbonylation of o-halobiaryls in the presence of palladium catalyst.
• Fused heterocycles (dihydrobenzofurans and indolines) from o-bromo phenol and aniline precursors via Pd-catalyzed intramolecular coupling of two C(sp3)-H bonds.
• Amides and esters derivatives containing a quaternary β-carbon atom by Pd-catalyzed C-H activation and amino/alkoxycarbonylation reaction.

It can also be used as a base in the palladium-catalyzed Mizoroki-Heck reaction.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves