679453

2-(Bromomethyl)phenylboronic acid

• Synonyme(s) : α-Bromo-o-tolueneboronic acid, o-Boronobenzyl bromide
• Formule empirique (notation de Hill): C₇H₈BBrO₂
• Numéro CAS: 91983-14-1
• Poids moléculaire : 214.85
• Numéro MDL: MFCD01318941
• Code UNSPSC : 12352103
• ID de substance PubChem : 24885495
• Nomenclature NACRES : NA.22

Propriétés

• Pf: 158-162 °C
• Niveau de qualité: 100
• Groupe fonctionnel: bromo
• Température de stockage: 2-8°C
• Chaîne SMILES: OB(O)c1ccccc1CBr
• InChI: 1S/C7H8BBrO2/c9-5-6-3-1-2-4-7(6)8(10)11/h1-4,10-11H,5H2
• Clé InChI: MYVJCOQGXCONPE-UHFFFAOYSA-N

Description

Description générale

May contain varying amounts of anhydride.

Application

2-(Bromomethyl)phenylboronic acid can be used as a reactant to synthesize:

• Boronic acid-functionalized benzyl viologen (o-BBV) from 4,4′-bipyridine. o-BBV finds its application as a chemosensor to sense glucose in aqueous water.
• 2-(azidomethyl)phenylboronic acid, which is further employed in the preparation of isoquinoline derivatives.
• Aryl boronic acid derivatives as fluorescent probe for hydrogen peroxide detection.

Reactant involved in:

• Studies of carbon-boron bond cleavage of phenylboronate-pendant cyclen
• Development of a sensory system to detect glucose or other monosaccharides and hydroxycarboxylates
• Synthesis of boronated triaryl and tetraaryl phosphonium salts used in cytotoxicity studies
• Colorimetry and fluorometry mercury determination with chemosensors composed of rhodamine and boronic acid groups
• Synthesis of imidazolium-containing boronic acids used as fluoride ion sensors
• Reactions with adenine for molecules with antiinflammatory antitumor activities 

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves