415057

Magnesium stearate

technical grade

• Synonyme(s) : Stearic acid magnesium salt
• Formule linéaire : [CH₃(CH₂)₁₆CO₂]₂Mg
• Numéro CAS: 557-04-0
• Poids moléculaire : 591.24
• Numéro Beilstein : 3919702
• Numéro CE : 209-150-3
• Numéro MDL: MFCD00036391
• Code UNSPSC : 12352100
• ID de substance PubChem : 24865972
• Nomenclature NACRES : NA.22

Propriétés

• Qualité: technical grade
• Niveau de qualité: 100
• Forme: powder
• Composition: palmitate salt, 25% ; stearate salt, 65%
• Pf: 200 °C (lit.)
• Chaîne SMILES: CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC
• InChI: 1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
• Clé InChI: HQKMJHAJHXVSDF-UHFFFAOYSA-L

Description

Description générale

Magnesium stearate (Mg-St) is the magnesium salt of stearic acid. Its anhydrate, dihydrate and trihydrate forms have been prepared. The tabletting of the blends of magnesium stearate and lactose granules has been described. The influence of mixing time on hardness, disintegration time and ejection force on the compressed tablets was examined. Mg-St is widely used lubricant in pharmaceutical industry. It also plays a role in delaying the process of dissolution. Its detection in tablets by laser-induced breakdown spectroscopy has been proposed.

Magnesium stearate, the salt of stearic acid, is widely employed as an inactive component in making pharmaceutical tablets.

Application

Magnesium stearate may be used as excipient in the formulations of diclofenac sodium tablets. It may be used for the preparation of tramadol HCl matrix tablets.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves