302120

n-Butyllithium solution

2.0 M in cyclohexane

• Synonyme(s) : n-BuLi, Butyl lithium, Butyllithium solution, Lithium-1-butanide
• Formule linéaire : CH₃(CH₂)₃Li
• Numéro CAS: 109-72-8
• Poids moléculaire : 64.06
• Numéro Beilstein : 1209227
• Numéro MDL: MFCD00009414
• Code UNSPSC : 12352103
• ID de substance PubChem : 24858234
• Nomenclature NACRES : NA.22

Propriétés

• Forme: liquid
• Niveau de qualité: 200
• Concentration: 2.0 M in cyclohexane
• Point d'ébullition: 80 °C
• Densité: 0.775 g/mL at 25 °C
• Température de stockage: 2-8°C
• Chaîne SMILES: [Li]CCCC
• InChI: 1S/C4H9.Li/c1-3-4-2;/h1,3-4H2,2H3;
• Clé InChI: MZRVEZGGRBJDDB-UHFFFAOYSA-N

Description

Description générale

n-Butyllithium (n-BuLi) is an organolithium reagent widely used as a strong base (superbase) in organic synthesis for the preparation of various chemical intermediates. It is also used as a reagent for lithium-halogen exchange and lithium-metal transmetalation reactions. n-BuLi is capable of lithiating carbon acids.

Application

n-Butyllithium (2.0 M in cyclohexane) can be used as:      

• A polymerization initiator to synthesize polystyrenes by anionic polymerization of styrene.      
• A strong base in the diastereoselective alkylation reactions.
• A reagent to synthesize 2-benzoylpyrroles by reacting benzaldehydes with di(1H-pyrrol-1-yl)zirconium(IV) chloride complex.

Conditionnement

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Informations légales

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Informations sur la sécurité

• Pictogrammes: GHS02,GHS08,GHS05,GHS07,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H225,H260,H304,H314,H336,H410
• Conseils de prudence: P210 - P231 + P232 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react 1
• Organes cibles: Central nervous system
• Risques supp: EUH014
• Code de la classe de stockage: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): -0.4 °F - closed cup
• Point d'éclair (°C): -18 °C - closed cup
• Équipement de protection individuelle: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter