298891

(4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinone

99%

• Synonyme(s) : (4R,5S)-4-Methyl-5-phenyl-2-oxazolidinone
• Formule empirique (notation de Hill): C₁₀H₁₁NO₂
• Numéro CAS: 77943-39-6
• Poids moléculaire : 177.20
• Numéro Beilstein : 1211705
• Numéro MDL: MFCD00010845
• Code UNSPSC : 12352005
• ID de substance PubChem : 24858003
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: 99%
• Forme: solid
• Activité optique: [α]18/D +168°, c = 2 in chloroform
• Pureté optique: ee: 98% (GLC)
• Pf: 121-123 °C (lit.)
• Chaîne SMILES: C[C@H]1NC(=O)O[C@H]1c2ccccc2
• InChI: 1S/C10H11NO2/c1-7-9(13-10(12)11-7)8-5-3-2-4-6-8/h2-7,9H,1H3,(H,11,12)/t7-,9-/m1/s1
• Clé InChI: PPIBJOQGAJBQDF-VXNVDRBHSA-N

Description

Application

Evan′s chiral auxiliary (4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinone reacts with carboxylic acids to produce corresponding acyl derivatives in the presence of a diisopropylcarbodiimide reagent. It can also employed in the preparation of N-sulfinyloxazolidinone reagent (chiral sulfinyl transfer reagent), which reacts with nucleophiles such as Grignard reagents, enolates, and metalated amides to produce the chiral sulfoxides, sulfinate esters, and sulfonamides.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)