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290858

Sigma-Aldrich

Nonylphenol

technical grade, mixture of ring and chain isomers

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About This Item

Formule empirique (notation de Hill):
C15H24O
Numéro CAS:
Poids moléculaire :
220.35
Numéro Beilstein :
2047450
Numéro CE :
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22

Qualité

technical grade

Indice de réfraction

n20/D 1.511 (lit.)

Solubilité

water: slightly soluble 4.9 mg/L±0.4 mg/L

Densité

0.937 g/mL at 25 °C (lit.)

Chaîne SMILES 

CCCCCCCCCc1ccc(O)cc1

InChI

1S/C15H24O/c1-13(2)7-5-3-4-6-8-14-9-11-15(16)12-10-14/h9-13,16H,3-8H2,1-2H3

Clé InChI

JSFITYFUKSFPBZ-UHFFFAOYSA-N

Informations sur le gène

mouse ... Esr1(13982)
rat ... Ar(24208)

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Description générale

Nonylphenol is a toxic xenobiotic compound classified as an endocrine disrupter capable of interfering with the hormonal system of numerous organisms. Nonylphenol has been reported as antiandrogen by using a yeast detection system. Molecular mechanism for the antiandrogenic action of nonylphenol has been reported.

Application

  • Chlorination of Emerging Contaminants for Application in Potable Wastewater Reuse: Disinfection Byproduct Formation, Estrogen Activity, and Cytotoxicity.: Investigates the formation of disinfection byproducts, estrogen activity, and cytotoxicity during chlorination of nonylphenol in potable wastewater reuse applications, offering insights into water treatment safety protocols (Cochran et al., 2024).
  • Triple-Mode Sensor Coupled by Photoelectrochemical, Electrochromic, and Spectral Signals for Sensitive Visualized Detection of Nonylphenol.: Describes the development of a sensitive triple-mode sensor for detecting nonylphenol, integrating photoelectrochemical, electrochromic, and spectral signals, which could be instrumental in environmental monitoring and industrial process controls (Cao et al., 2023).

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

>235.4 °F - closed cup

Point d'éclair (°C)

> 113 °C - closed cup

Équipement de protection individuelle

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Consulter la Bibliothèque de documents

A Soares et al.
Environment international, 34(7), 1033-1049 (2008-02-20)
Nonylphenol is a toxic xenobiotic compound classified as an endocrine disrupter capable of interfering with the hormonal system of numerous organisms. It originates principally from the degradation of nonylphenol ethoxylates which are widely used as industrial surfactants. Nonylphenol ethoxylates reach
Hyun Ju Lee et al.
Toxicological sciences : an official journal of the Society of Toxicology, 75(1), 40-46 (2003-06-14)
By using a yeast detection system for androgenic and antiandrogenic effects of chemicals, we identified bisphenol A (BPA) and nonylphenol (NP) as antiandrogens. In this study, we report molecular mechanisms for the antiandrogenic action of BPA and NP. In the
C Uguz et al.
Andrologia, 47(8), 910-919 (2014-10-04)
The objective of this study was to determine the effects of nonylphenol (NP) on viability of ram and boar sperm in vitro. Ram or boar spermatozoa were exposed to 1, 10, 100, 250 and 500 μg NP ml(-1) for 1, 2, 3 or
Maurizio Forte et al.
Ecotoxicology and environmental safety, 180, 412-419 (2019-05-21)
Estrogens play a role in the patho-physiology of the prostate. In the present work we studied the effects of nonylphenol (NP), a xenoestrogen, on human adenocarcinoma prostate cells (LNCaP). In order to understand molecular and cellular involvement, we observed the
Tomasz Janicki et al.
Bioresource technology, 200, 223-229 (2015-10-23)
Nonylphenol (NP), 4-tert-octylphenol (4-t-OP) and 4-cumylphenol (4-CP) are pollutants that are known as endocrine disruptors mainly due to their estrogen-mimicking activity. These phenolic substances are used in a wide range of industrial and commercial applications. In the present study, biodegradation

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