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202371

Sigma-Aldrich

Poly(éthylène glycol)

average Mn 300, hydroxyl

Synonyme(s) :

PEG

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About This Item

Formule linéaire :
H(OCH2CH2)nOH
Numéro CAS:
25322-68-3
Numéro MDL:
MFCD00081839
Code UNSPSC :
12352104
ID de substance PubChem :
24852059
Nomenclature NACRES :
NA.23

product name

Poly(éthylène glycol), average Mn 300

Forme

viscous liquid

Niveau de qualité

200

Poids mol.

Mn 285-315
average Mn 300

Indice de réfraction

n20/D 1.463

pH

6-7 (23 °C, at 10 g/l)

Viscosité

5.8 cSt(210 °F)(lit.)

Pf

−15-−8 °C (lit.)

Densité

1.125 g/mL at 25 °C

Mw/Mn

1.1 (typical)

Extrémité Ω

hydroxyl

Extrémité α

hydroxyl

Chaîne SMILES 

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Clé InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Catégories apparentées

Description générale

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks, PEG can have high water content, forming "hydrogels". Hydrogel formation can be initiated by either crosslinking PEG by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends. PEG is a suitable material for biological applications because it does not trigger an immune response.

Application


  • PEG modification increases thermostability and inhibitor resistance of Bst DNA polymerase.: This study demonstrates that polyethylene glycol (PEG) modification significantly enhances the thermostability and inhibitor resistance of Bst DNA polymerase, highlighting PEG′s potential in improving enzyme performance for biotechnological applications (Yang et al., 2024).

  • Development of Lyophilized Eukaryotic Cell-Free Protein Expression System Based on Leishmania tarentolae.: The incorporation of PEG in the lyophilization process of a cell-free protein expression system demonstrates its role in enhancing the stability and efficiency of biotechnological workflows (Alfaro-Palma et al., 2024).

  • A comprehensive review on singlet oxygen generation in nanomaterials and conjugated polymers for photodynamic therapy in the treatment of cancer.: This review highlights the application of PEGylated nanomaterials in photodynamic therapy, emphasizing its significance in improving biocompatibility and therapeutic efficacy in cancer treatments (Singh et al., 2024).


Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

428.0 °F - closed cup

Point d'éclair (°C)

220.00 °C - closed cup

Équipement de protection individuelle

Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
BCCG7497
BCCG7496
BCCF9465
BCCF0485
BCCF0486

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Consulter la Bibliothèque de documents

Plasticizing collagen hydrolysate with glycerol and low-molecular weight poly(ethylene glycols)
Langmaier F, et al.
Thermochimica Acta, 469(1-2), 52-58 (2008)
Developing perylene diimide based acceptor polymers for organic photovoltaics
Liang Z, et al.
Synthetic Metals, 161(11-12), 1014-1021 (2011)
Anju Singh et al.
Scientific reports, 10(1), 3766-3766 (2020-03-01)
Th17 cells are critical drivers of autoimmune diseases and immunopathology. There is an unmet need to develop therapies targeting pathogenic Th17 cells for the treatment of autoimmune disorders. Here, we report that anxiolytic FGIN-1-27 inhibits differentiation and pathogenicity of Th17
Rheological studies of disulfonated poly(arylene ether sulfone) plasticized with poly(ethylene glycol) for membrane formation
Oh HJ, et al.
Polymer, 55(6), 1574-1582 (2014)
Ofer Beharier et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(44), 27319-27328 (2020-10-23)
The recently identified ferroptotic cell death is characterized by excessive accumulation of hydroperoxy-arachidonoyl (C20:4)- or adrenoyl (C22:4)- phosphatidylethanolamine (Hp-PE). The selenium-dependent glutathione peroxidase 4 (GPX4) inhibits ferroptosis, converting unstable ferroptotic lipid hydroperoxides to nontoxic lipid alcohols in a tissue-specific manner.
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