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Key Documents

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181285

Sigma-Aldrich

Poly(acrylic acid)

average Mv ~450,000

Synonyme(s) :

PAA

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About This Item

Formule linéaire :
(C3H4O2)n
Numéro CAS:
9003-01-4
Numéro MDL:
MFCD00084394
Code UNSPSC :
12162002
ID de substance PubChem :
24850924
Nomenclature NACRES :
NA.23

Réticulation

~0.1 % cross-linked

Poids mol.

average Mv ~450,000

Viscosité

350-2500 cP

Température de transition

Tg 106 °C

InChI

1S/C3H4O2.Na/c1-2-3(4)5;/h2H,1H2,(H,4,5);/q;+1/p-1

Clé InChI

NNMHYFLPFNGQFZ-UHFFFAOYSA-M

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Description générale

Poly (acrylic acid) (PAA) is hygroscopic, brittle and colorless in nature with Tg at nearly 106oC. At temperatures above 200 to 250oC, it loses water and becomes an insoluble crosslinked polymer anhydride. Solubility of dried PAA in water increases with rise in temperatures. Concentrated solutions of PAA in water is thixotropic in nature.

Application

Poly (acrylic acid) (PAA)/Poly methyl methacrylate copolymers are used for drug delivery.
Other applications may include:
  • to study solute diffusion in Polyvinyl alcohol/PAA copolymer hydrogel
  • synthesizing poly(N-isopropylacrylamide)-block-PAA copolymer which responds to both temperature and pH stimuli
  • in preparing block copolymer of oligo (methyl methacrylate)/PAA for micellar delivery of hydrophobic drugs
  • as thickening agent for adhesives.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Synthesis and characterization of P (MMA-AA) copolymers for targeted oral drug delivery.
Barba AA, et al.
Polymer Bull., 62(5), 679-688 (2009)
Solute diffusion in poly (vinyl alcohol)/poly (acrylic acid) interpenetrating networks.
Peppas NA, et al.
Macromolecules, 29(27), 8798-8804 (1996)
Christina M Kelliher et al.
Fungal biology, 124(5), 398-406 (2020-05-12)
Work on the filamentous fungus Neurospora crassa has contributed to or pioneered many aspects of research on circadian clock mechanism, a process that is functionally conserved across eukaryotes. Biochemical assays of the fungal circadian clock typically involve growth in liquid
T Inoue et al.
Journal of controlled release : official journal of the Controlled Release Society, 51(2-3), 221-229 (1998-08-01)
An AB block copolymer of oligo(methyl methacrylate) (oMMA) and poly(acrylic acid) (PAAc) has been synthesized. The block copolymer forms micelles in an aqueous medium, as confirmed by a fluorescence probe technique using pyrene. Doxorubicin hydrochloride was incorporated into the micelle
A New Double-Responsive Block Copolymer Synthesized via RAFT Polymerization: Poly (N-isopropylacrylamide)-b lock-poly (acrylic acid)
Schili CM, et al.
Macromolecules, 37(21), 7861-7866 (2004)
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