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Merck

MCL1

myeloid cell leukemia sequence 1 (BCL2-related)

Synonymes:
BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
Espèce(s):
Human MCL1 (4170), Mouse Mcl1 (17210), Rat Mcl1 (60430), sheep MCL1 (554329), domestic guinea pig Mcl1 (100721658), naked mole-rat Mcl1 (101724340), chicken MCL1 (395674), dog MCL1 (403537), domestic cat MCL1 (493970), cow MCL1 (788087)
ID UniProtKB:
Q07820, B2R6B2, D3DV03, D3DV04, Q9HD91, Q9NRQ3, Q9NRQ4, Q9UHR7
ID du gène:
  • Human(4170) Summary: This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]
  • Mouse(17210) myeloid cell leukemia sequence 1
  • Rat(60430) myeloid cell leukemia sequence 1
  • sheep(554329) myeloid cell leukemia sequence 1 (BCL2-related)
  • domestic guinea pig(100721658) myeloid cell leukemia sequence 1 (BCL2-related)
  • naked mole-rat(101724340) myeloid cell leukemia sequence 1 (BCL2-related)
  • chicken(395674) myeloid cell leukemia sequence 1 (BCL2-related)
  • dog(403537) myeloid cell leukemia sequence 1 (BCL2-related)
  • domestic cat(493970) myeloid cell leukemia sequence 1 (BCL2-related)
  • cow(788087) myeloid cell leukemia sequence 1 (BCL2-related)

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Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
G8761
(±)-Gossypol from cotton seeds, ≥95% (HPLC),
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA031125
Anti-MCL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
MABC43
Anti-Mcl-1 Antibody, clone RC13, clone RC13, from mouse,
Espèces réactives
human
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
AB2910
Anti-Mcl-1 Antibody, serum, Chemicon®,
Espèces réactives
human
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB4501843
Anti-MCL1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
western blot
SAB4501844
Anti-MCL1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot

esiRNA

Référence du produit
Description
Espèce(s)
EHU079921
MISSION® esiRNA, targeting human MCL1,
Espèce(s)
human
EMU064061
MISSION® esiRNA, targeting mouse Mcl1,
Espèce(s)
mouse