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ITGAV

integrin, alpha V

Synonymes:
CD51, MSK8, VNRA, VTNR
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • sheep(443143) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • Horse(100068706) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • dog(488437) integrin, alpha V
  • chicken(396420) integrin, alpha V

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Small Molecule - Antagonist

Product Number
Description
Espèce(s)
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
Espèce(s)
human

Antibodies

Product Number
Description
Espèces réactives
Application
αβ, clone 10D5, Chemicon®, from mouse,
Espèces réactives
human, mouse, rat
Application
flow cytometry
immunoprecipitation (IP)
Anticorps anti-intégrine αV β3, clone LM609, clone LM609, Chemicon®, from mouse,
Espèces réactives
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Application
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)
Anti-Integrin αV Antibody, clone LM142, ,
Espèces réactives
human
Application
flow cytometry
immunofluorescence

immunohistochemistry

neutralization
Anti-Integrin αV Antibody, clone LM142, ascites fluid, clone LM142, Chemicon®,
Espèces réactives
human
Application
immunohistochemistry
immunoprecipitation (IP)
Anticorps anti-intégrine αVβ3, clone LM609, sans azoture, clone LM609, Chemicon®, from mouse,
Espèces réactives
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Application
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

Proteins

Product Number
Description
Espèce(s)
Human Integrin αVβ3, Octyl-β-D-glucopyranoside Formulation, ,
Espèce(s)
human
Human Integrin αVβ3 Protein, Triton X-100 Formulation, ,
Espèce(s)
human

esiRNA

Product Number
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Itgav,
Espèce(s)
mouse
MISSION® esiRNA, targeting human ITGAV,
Espèce(s)
human