DNASE1
deoxyribonuclease I
Synonymes:
DNL1, DRNI
Espèce(s):
Human DNASE1 (1773), Mouse Dnase1 (13419), Rat Dnase1 (25633), Zebrafish dnase1 (436947), dog DNASE1 (403413), domestic cat DNASE1 (101096195), cow DNASE1 (282217), Horse DNASE1 (100034219), chicken DNASE1 (395725), sheep DNASE1 (101122154) ...Plus
ID UniProtKB:
ID du gène:
- Human(1773) Summary: This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
- Mouse(13419) deoxyribonuclease I
- Rat(25633) deoxyribonuclease I
- Zebrafish(436947) deoxyribonuclease I
- dog(403413) deoxyribonuclease I
- domestic cat(101096195) deoxyribonuclease I
- cow(282217) deoxyribonuclease I
- Horse(100034219) deoxyribonuclease I
- chicken(395725) deoxyribonuclease I
- sheep(101122154) deoxyribonuclease I
- Domestic Rabbit(100009513) deoxyribonuclease I
- naked mole-rat(101713435) deoxyribonuclease I
- domestic guinea pig(100718441) deoxyribonuclease I
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-DNASE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Anti-DNASE1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, human, rat
Application
western blot
Anti-DNASE1 (N-terminal) antibody produced in rabbit FITC conjugated, affinity isolated antibody,
Espèces réactives
bovine, human, rat
Application
Anti-DNASE1 (N-terminal) antibody produced in rabbit HRP conjugated, affinity isolated antibody,
Espèces réactives
bovine, human, rat
Application
Proteins
Référence du produit
Description
Espèce(s)
Désoxyribonucléase I from bovine pancreas, lyophilized powder, Protein ≥85 %, ≥400 Kunitz units/mg protein,
Espèce(s)
Désoxyribonucléase I from bovine pancreas, Type IV, lyophilized powder, ≥2,000 Kunitz units/mg protein,
Espèce(s)
Désoxyribonucléase I from bovine pancreas, Type II, lyophilized powder, Protein ≥80 %, ≥2,000 units/mg protein,
Espèce(s)
Désoxyribonucléase I from bovine pancreas, Type II-S, lyophilized powder, Protein ≥80 %, ≥2,000 units/mg protein,
Espèce(s)
DNase I recombinant, grade I, from bovine pancreas, expressed in Pichia pastoris,
Espèce(s)
cow