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Merck

DDR1

discoidin domain receptor tyrosine kinase 1

Synonymes:
CAK, CD167, DDR, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE
Espèce(s):
Human DDR1 (780), Mouse Ddr1 (12305), Rat Ddr1 (25678), Zebrafish ddr1 (100007346), cow DDR1 (534092), Horse DDR1 (100050861), domestic cat DDR1 (101096728), dog DDR1 (474832), domestic guinea pig Ddr1 (100725492), naked mole-rat Ddr1 (101699683)
ID UniProtKB:
Q08345, B5A975, B5A976, B7Z2K0, Q14196, Q16562, Q2L6H3, Q4LE50
ID du gène:
  • Human(780) Summary: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(12305) discoidin domain receptor family, member 1
  • Rat(25678) discoidin domain receptor tyrosine kinase 1
  • Zebrafish(100007346) discoidin domain receptor family, member 1
  • cow(534092) discoidin domain receptor tyrosine kinase 1
  • Horse(100050861) discoidin domain receptor tyrosine kinase 1
  • domestic cat(101096728) discoidin domain receptor tyrosine kinase 1
  • dog(474832) discoidin domain receptor tyrosine kinase 1
  • domestic guinea pig(100725492) discoidin domain receptor tyrosine kinase 1
  • naked mole-rat(101699683) discoidin domain receptor tyrosine kinase 1
  • sheep(101104279) discoidin domain receptor tyrosine kinase 1

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ELISA

Product Number
Description
Espèce(s)
RAB1412
Human DDR1 ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Product Number
Description
Espèces réactives
Application
SAB4504671
Anti-phospho-DDR1 (pTyr513) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
MABT333
Anti-CD167a/DDR1 Antibody, clone 5D5, clone 5D5, from mouse,
Espèces réactives
human
Application
flow cytometry
immunocytochemistry
ZRB2086
Anti-CD167a/DDR1 Antibody, clone 1D11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, human, monkey, mouse, porcine, rat
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
SAB5700578
Anti-Phospho-DDR1-Y792 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
western blot
SAB2900058
Anti-DDR1 (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
bovine, dog, horse, human, monkey, pig
Application
immunohistochemistry

Proteins

Product Number
Description
Espèce(s)
SRP5020
DDR1 (444-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Product Number
Description
Espèce(s)
EMU045291
MISSION® esiRNA, targeting mouse Ddr1,
Espèce(s)
mouse
EHU113231
MISSION® esiRNA, targeting human DDR1,
Espèce(s)
human