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Key Documents

TOX2

Sigma-Aldrich

In Vitro Toxicology Assay Kit, XTT based

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About This Item

UNSPSC Code:
12352207

form

solid

usage

 kit sufficient for 1,000 tests

packaging

pkg of 1 kit

storage condition

dry at room temperature

λmax

450 nm

application(s)

cell analysis
detection

detection method

colorimetric

storage temp.

−20°C

Application

For spectrophotometric measurement of cell viability by mitochodrial dehydrogenase. Absorbance of converted dye is measured at a wavelength of 450 nm.

Biochem/physiol Actions

Conversion of XTT to a water-soluble colored formazan derivative.

Pictograms

Flame

Signal Word

Danger

Hazard Statements

Hazard Classifications

Self-react. C

Supplementary Hazards

Storage Class Code

4.1A - Other explosive hazardous materials

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Raymond W Wong et al.
PLoS pathogens, 9(3), e1003241-e1003241 (2013-04-05)
To develop new approaches to control HIV-1 replication, we examined the capacity of recently described small molecular modulators of RNA splicing for their effects on viral RNA metabolism. Of the drugs tested, digoxin was found to induce a dramatic inhibition
Catherine Gerard et al.
Cell transplantation, 21(1), 127-137 (2011-05-04)
Duchenne muscular dystrophy (DMD) is the most frequent muscular dystrophy in children and young adults. Currently, there is no cure for the disease. The transplantation of healthy myoblasts is an experimental therapeutic strategy, since it could restore the expression of
Queenie P Vong et al.
Blood, 124(26), 3905-3913 (2014-10-30)
Thymocyte selection-associated high mobility group box protein family member 2 (TOX2) is a transcription factor belonging to the TOX family that shares a highly conserved high mobility group DNA-binding domain with the other TOX members. Although TOX1 has been shown
Sandrine Chabane et al.
Applied and environmental microbiology, 72(5), 3259-3267 (2006-05-05)
ECM33 encodes a glycosylphosphatidylinositol-anchored protein whose orthologs in yeast are essential for sporulation. Aspergillus fumigatus Ecm33p is unique and has an apparent mass of 55 kDa. Disruption of A. fumigatus ECM33 results in a mutant with several morphogenetic aberrations, including
Eunsohl Lee et al.
Journal of cellular biochemistry, 117(12), 2815-2824 (2016-05-07)
Prostate cancer (PCa) is known to develop resistance to chemotherapy. Growth arrest-specific 6 (GAS6), plays a role in tumor progression by regulating growth in many cancers. Here, we explored how GAS6 regulates the cell cycle and apoptosis of PCa cells

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