SML3472

ATR-002

≥98% (HPLC)

• Synonym(s): Benzoic acid, 2-[(2-chloro-4-iodophenyl)amino]-3,4-difluoro- (9CI, ACI)
• Empirical Formula (Hill Notation): C₁₃H₇ClF₂INO₂
• CAS Number: 303175-44-2
• Molecular Weight: 409.55
• MDL number: MFCD09840238
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C(C1=CC=C(C(F)=C1NC2=CC=C(C=C2Cl)I)F)O
• InChI: 1S/C13H7ClF2INO2/c14-8-5-6(17)1-4-10(8)18-12-7(13(19)20)2-3-9(15)11(12)16/h1-5,18H,(H,19,20)

Description

Biochem/physiol Actions

ATR-002, a derivate of CI-1040, is a cell penetrant, potent and specific inhibitor of the Raf/MEK/ERK pathway. ATR-002 exhibits strong anti-influenza and anti-SARS-CoV-2 activity. It impairs the influenzas and SARS-CoV-2 viruses induced expression of pro-inflammatory cytokines.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable