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Key Documents

SAB4701049

Sigma-Aldrich

Monoclonal Anti-RLTPR antibody produced in mouse

clone EM-53

Synonym(s):

CARMIL2, LRRC16C

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

EM-53, monoclonal

form

buffered aqueous solution

concentration

1 mg/mL

technique(s)

flow cytometry: 2 μg/mL

accession no.

Q6F5E8

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

General description

The mouse monoclonal antibody EM-53 recognizes RLTPR / CARMIL2, a protein playing a role in actin filament elongation.

Immunogen

Murine RLTPR

Physical form

Solution in phosphate buffered saline with 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Jennifer R Yonkof et al.
Frontiers in immunology, 11, 884-884 (2020-07-07)
CARMIL2 deficiency is a rare combined immunodeficiency (CID) characterized by defective CD28-mediated T cell co-stimulation, altered cytoskeletal dynamics, and susceptibility to Epstein Barr Virus smooth muscle tumors (EBV-SMTs). Case reports associated with EBV-SMTs are limited. We describe herein a novel

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