SAB4300278

Anti-phospho-CCNB1 (pSer¹⁴⁷) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-CCNB antibody produced in rabbit, Anti-cyclin B1 antibody produced in rabbit
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~60 kDa
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (A-F-SP-D-V)
• NCBI accession no.: NP_114172.1
• UniProt accession no.: P14635
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer147)
• Gene Information: human ... CCNB1(891)

Description

Immunogen

Peptide sequence around phosphorylation site of serine 147 (A-F-S(p)-D-V), according to the protein CCNB1.

Features and Benefits

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Target description

The protein encoded by Cyclin B1 is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable