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G7253

Sigma-Aldrich

Ginseng root from Panax quinquefolium (American ginseng)

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.81

biological source

Panax quinquefolium

Quality Level

200

form

powder

General description

Ginseng comprises of saponins called ginsenosides, acidic polysaccharides and polyphenolic compounds.
Ginseng is an important herbal remedy extensively used to improve cardiac health and circulation. Treatment with Panax ginseng has shown to improve cardiac performance. It also increases protection against myocardial ischemia/reperfusion damage by enhancing nitric oxide (NO) release.

Application

American ginseng (Panax quinquefolium) was used to test its protective effects against mitomycin C induced micronuclei in mice. It is used to test the adaptogenic and anti-amnesic properties of evolvulus alsinoides in rodents.
Ginseng root from Panax quinquefolium (American ginseng) has been used as control in hyperlocomotor activity studies and adaptogenic activity screening in mice.

Biochem/physiol Actions

Ginseng is an effective immune modulator and improves phagocytic functionality of macrophages and stimulates natural killer cells. Ginseng elicits anticancer and anti-diabetic functionality. Ginseng may provide protection in neurodegenerative diseases like Parkinson′s disease and Alzheimer′s disease. Ginseng improves liver regeneration and is effective in treating hepatocellular carcinoma.

Quality

Crude powder

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
061K1145V
081H0043
061K1145

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Amol Ashok Pawar et al.
Phytotherapy research : PTR, 21(12), 1221-1227 (2007-07-31)
Mitomycin C (MMC) is a highly active anticancer drug commonly used alone and in combination with other chemotherapeutic agents for the treatment of different cancers. Its bioactivated form critically damages the DNA present in both rapidly dividing cancerous cells as
Ginseng, the'immunity boost': the effects of Panax ginseng on immune system
Kang S and Min H
Journal of ginseng research, 36(4), 354-354 (2012)
Pharmacological effects of ginseng on liver functions and diseases: a minireview
Huu TN, et al.
Evidence-Based Complementary and Alternative Medicine : ECAM, 2012 (2012)
Kiran Babu Siripurapu et al.
Pharmacology, biochemistry, and behavior, 81(3), 424-432 (2005-05-19)
Evolvulus alsinoides (EA) is well known for its memory enhancement, antiepileptic and immunomodulatory properties in the traditional Indian system of medicine, Ayurveda. In view of the increasing attention towards plants offering non-specific resistance (adaptogens) towards stress, we have evaluated crude
Evaluation of the antipsychotic potential of Panax quinquefolium in ketamine induced experimental psychosis model in mice
Chatterjee M, et al.
Neurochemical Research, 37(4), 759-770 (2012)
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Articles

HPLC Separation of Ginsenosides from American Ginseng

The HPLC method for ginsenoside separation was optimized using a ginsenoside standard mixture and then applied to a sample of American Ginseng root. The experimental conditions and chromatograms are shown.

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