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A1394

Sigma-Aldrich

4-Aminophenyl α-D-mannopyranoside

≥98% (TLC)

Synonym(s):

p-aminophenyl alpha-D-mannoside

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About This Item

Empirical Formula (Hill Notation):
C12H17NO6
CAS Number:
Molecular Weight:
271.27
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

≥98% (TLC)

form

powder

optical activity

[α]/D 123.00 to 135.00°, c = 9.00-11.00 mg/mL in methanol

technique(s)

thin layer chromatography (TLC): suitable

color

white to yellow cast

solubility

H2O: soluble

storage temp.

2-8°C

SMILES string

Nc1ccc(OC2OC(CO)C(O)C(O)C2O)cc1

InChI

1S/C12H17NO6/c13-6-1-3-7(4-2-6)18-12-11(17)10(16)9(15)8(5-14)19-12/h1-4,8-12,14-17H,5,13H2

InChI key

MIAKOEWBCMPCQR-UHFFFAOYSA-N

Application

4-Aminophenyl α-D-mannopyranoside is used to modify the surface of liposomes to increase uptake kinetics.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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K Shimura et al.
Journal of chromatography, 400, 353-359 (1987-07-29)
Affinophoresis is an electrophoretic separation technique for biological polymers with the aid of an affinophore, which is a macromolecular polyelectrolyte bearing affinity ligands. The affinophore migrates rapidly in an electric field, and consequently the electrophoretic mobility of molecules having an
K Shimura et al.
Journal of biochemistry, 120(6), 1146-1152 (1996-12-01)
Affinophoresis is a type of affinity electrophoresis in which an affinophore, a conjugate of an affinity ligand and a multiply charged soluble matrix, causes a change in migration velocity of proteins which have a specific affinity for the ligand. A
Sumio Chono et al.
The Journal of pharmacy and pharmacology, 59(1), 75-80 (2007-01-18)
The influence of particle size and surface mannose modification on the uptake of liposomes by alveolar macrophages (AMs) was investigated in-vitro and in-vivo. Non-modified liposomes of five different particle sizes (100, 200, 400, 1000 and 2000 nm) and mannosylated liposomes
P K Das et al.
Experientia, 38(5), 629-630 (1982-05-15)
Antiserum was raised against an aminophenyl derivative of D-mannose grafted on to a liposomal surface. As characterized by immunodiffusion, quantitative precipitation and hapten inhibition, the antiserum was found to contain mannose specific antibodies in addition to antibodies against the aromatic
Sofie Tanghe et al.
Molecular reproduction and development, 67(2), 224-232 (2003-12-25)
Several steps in the process of mammalian fertilization are mediated by carbohydrates. This study investigated the role of the p-aminophenyl derivative of d-mannose (APMP) during bovine fertilization. Inseminating cumulus-oocyte complexes (COCs) in the presence of increasing APMP concentrations resulted in

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