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78832

Sigma-Aldrich

D-Sedoheptulose 7-phosphate lithium salt

≥90% (TLC)

Synonym(s):

D-altro-Heptulose 7-phosphate lithium salt

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About This Item

Empirical Formula (Hill Notation):
C7H15O10P · xLi+
CAS Number:
Molecular Weight:
290.16 (free acid basis)
UNSPSC Code:
12352201
NACRES:
NA.25

Quality Level

Assay

≥90% (TLC)

form

powder

color

white to light yellow

storage temp.

−20°C

InChI

1S/C7H15O10P/c8-1-3(9)5(11)7(13)6(12)4(10)2-17-18(14,15)16/h4-8,10-13H,1-2H2,(H2,14,15,16)/t4-,5-,6-,7+/m1/s1

InChI key

JDTUMPKOJBQPKX-GBNDHIKLSA-N

Biochem/physiol Actions

D-Sedoheptulose 7-phosphate is a metabolite in a number of pathways, e.g. an intermediate in the pentose phosphate pathway, and the carbon fixation in photosynthetic organisms.
D-Sedoheptulose is a pentose phosphate pathway (PPP) intermediate. D-Sedoheptulose-7-phosphate contributes to the generation of NADPH and the formation of ribose residues of nucleotide synthesis. Sedoheptulose-7-phosphate levels may be increased in individuals with defects in transaldolase (TALSDO1).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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L Eidels et al.
Proceedings of the National Academy of Sciences of the United States of America, 68(8), 1673-1677 (1971-08-01)
Genetic and biochemical evidence that sedoheptulose-7-phosphate is an obligatory precursor of the L-glycero-D-mannoheptose residues of the lipopolysaccharide of Salmonella was obtained by isolation and characterization of transketolase-negative mutants of Salmonella typhimurium. These mutants, which are defective in synthesis of sedoheptulose-7-phosphate
Csörsz Nagy et al.
Biochemical Society transactions, 41(2), 674-680 (2013-03-22)
Dynamic carbon re-routing between catabolic and anabolic metabolism is an essential element of cellular transformation associated with tumour formation and immune cell activation. Such bioenergetic adaptations are important for cellular function and therefore require tight control. Carbohydrate phosphorylation has been
John F Williams et al.
Photosynthesis research, 90(2), 125-148 (2006-12-13)
14C-Labelled octulose phosphates were formed during photosynthetic 14CO2 fixation and were measured in spinach leaves and chloroplasts. Because mono- and bisphosphates of D: -glycero- D: -ido-octulose are the active 8-carbon ketosugar intermediates of the L-type pentose pathway, it was proposed
Biosynthesis of 4-hydroxy-2(or 5)-ethyl-5(or 2)-methyl-3(2H)-furanone by yeasts.
Sasaki, M., et al.
Journal of Agricultural and Food Chemistry, 39, 934-938 (1991)
Mirjam M C Wamelink et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 823(1), 18-25 (2005-08-02)
We describe a liquid chromatography tandem mass spectrometry (LC-MS/MS) method to quantify pentose phosphate pathway intermediates (triose-3-phosphates, tetrose-4-phosphate, pentose-5-phosphate, pentulose-5-phosphates, hexose-6-phosphates and sedoheptulose-7-phosphate (sed-7P)) in bloodspots, fibroblasts and lymphoblasts. Liquid chromatography was performed using an ion pair loaded C(18) HPLC

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