M3634
Manganese(II) chloride tetrahydrate
ReagentPlus®, ≥99%
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About This Item
Linear Formula:
MnCl2 · 4H2O
CAS Number:
Molecular Weight:
197.91
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.21
Assay:
≥99%
form:
powder
Recommended Products
Quality Level
product line
ReagentPlus®
Assay
≥99%
form
powder
pH
3.5-6 (25 °C, 50 g/L)
mp
58 °C (lit.)
SMILES string
Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]
InChI
1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2
InChI key
CNFDGXZLMLFIJV-UHFFFAOYSA-L
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General description
Manganese(II) chloride tetrahydrate is the tetrahydrate form of manganese(II) chloride. It is used in the preparation of manganese-based hybrid compounds.
Application
Manganese(II) chloride tetrahydrate can be used:
- As a promoter to synthesize dihydropyrimidin-2(1H)-ones by the condensation of aldehyde, β-dicarbonyl compounds, and urea under microwave conditions.
- As a catalyst to synthesize dihydro-2-oxypyrrole derivatives via one-pot four-component domino condensation of dialkyl acetylenedicarboxylate, formaldehyde, and amines.
- To synthesize active manganese oxide with potential application as an oxidant in organic synthesis.
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2
Target Organs
Brain
Storage Class Code
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 2
Flash Point(F)
does not flash
Flash Point(C)
does not flash
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The aim of this study was to provide data on the dose dependence of manganese-enhanced MRI (MEMRI) in the visual pathway of experimental rats and to study the toxicity of MnCl₂ to the retina. Sprague-Dawley rats were intravitreally injected with
Marta Sidoryk-Wegrzynowicz et al.
Journal of neurochemistry, 122(4), 856-867 (2012-06-20)
Manganese (Mn) has been implicated in the impairment of the glutamate-glutamine cycling (GGC) by deregulation of Glu and glutamine (Gln) turnover in astrocytes. Here, we have examined possible mechanisms involved in the Mn(II)-mediated disruption of Glu turnover, including those related
Tameshwar Ganesh et al.
Journal of magnetic resonance imaging : JMRI, 41(3), 806-813 (2014-03-05)
To investigate the potential of manganese (Mn)-enhanced MRI for sensitive detection and delineation of tumors that demonstrate little enhancement on Gd-DTPA. Eighteen nude rats bearing 1 to 2 cm in diameter orthotopic breast tumors (ZR75 and LM2) were imaged on
Jerome A Roth et al.
Neurotoxicology, 35, 121-128 (2013-01-15)
Chronic exposure to Mn results in the development of a neurological disorder known as manganism characterized by neurological deficits resembling that seen in Parkinsonism. Although dopaminergic neurons within the nigrostriatal pathway appear intact, Mn-induced irregularities in DA transmission have been
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