G0750
D-(+)-Galactose
≥99% (HPLC)
Synonym(s):
Galactose
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All Photos(8)
About This Item
Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
Beilstein:
1724619
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.21
biological source
bovine (Ruminant- Cow, Ox, Buffalo)
Quality Level
Assay
≥99% (HPLC)
form
powder
technique(s)
HPLC: suitable
impurities
≤0.1% glucose
color
white
useful pH range
5.0-7 (25 °C, 180 g/L)
mp
168-170 °C (lit.)
solubility
H2O: soluble 100 mg/mL, clear, colorless
storage temp.
room temp
SMILES string
OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O
InChI
1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6-/m0/s1
InChI key
GZCGUPFRVQAUEE-KCDKBNATSA-N
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Application
Galactose has been used:
- as a component of galactosyltransferase labeling buffer.
- as a supplement in MRS broth for the growth of thermophilic lactobacilli
- to induce the expression of uncoupling protein (UCP) in yeast transformants
Biochem/physiol Actions
Galactose is a simple monosaccharide that serves as an energy source and as an essential component of glycolipids and glycoproteins. Galactose contributes to energy metabolism via its conversion to glucose by the enzymes that constitute the Leloir pathway. Defects in the genes encoding these proteins lead to the metabolic disorder galactosemia.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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K W Turner et al.
Applied and environmental microbiology, 45(6), 1932-1934 (1983-06-01)
The ability to ferment galactose is a major characteristic which can be used to differentiate Lactobacillus helveticus (galactose positive) from Lactobacillus lactis and Lactobacillus bulgaricus (galactose negative). In milk cultures, galactose-positive strains produced d- and l-lactic acid with little galactose
D L Murdza-Inglis et al.
The Journal of biological chemistry, 269(10), 7435-7438 (1994-03-11)
The uncoupling protein is one of a family of mitochondrial transport proteins involved in energy metabolism. It dissipates oxidative energy to generate heat, either by catalyzing proton transport directly or by catalyzing fatty acid anion transport, thus enabling fatty acids
Lin Li et al.
Aging, 11(21), 9348-9368 (2019-11-13)
Gut dysbiosis and oxidative stress may trigger senile osteoporosis. Fructus Ligustri Lucidi (FLL) has bone-preserving properties and affects the intestinal microecology. However, the mechanism of the anti-osteoporotic effect of FLL and its link to the gut microbiota remains to be
Inge E Krabbendam et al.
Cell death & disease, 11(4), 263-263 (2020-04-25)
Metabolic flexibility is an essential characteristic of eukaryotic cells in order to adapt to physiological and environmental changes. Especially in mammalian cells, the metabolic switch from mitochondrial respiration to aerobic glycolysis provides flexibility to sustain cellular energy in pathophysiological conditions.
Anouk Zaal et al.
Frontiers in immunology, 11, 305-305 (2020-03-13)
Many tumors display alterations in the biosynthetic pathways of glycosylation, resulting in increased expression of specific tumor-associated glycan structures. Expression of these altered glycan structures is associated with metastasis and poor prognosis. Antigen presenting cells can recognize tumor-associated glycan structures
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