ABF13

Anti-Interleukin-10 Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: mouse, human
• technique(s): western blot: suitable
• NCBI accession no.: NP_034678
• UniProt accession no.: P18893
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... IL10(3586)

Description

General description

Interleukin-10 (IL-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF) is an 18.7 kDa protein of 160 amino acid residues that shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI. IL-10 down regulates the expression of Th1 cytokines, major histocompatibility complex class II antigens, and costimulatory molecules on macrophages. It also enhaces B cell survival, proliferation, and antibody production. Knockout studies suggest that IL-10 is an immunoregulator in the intestinal tract.

Immunogen

GST-tagged recombinant protein corresponding to mouse Interleukin-10.

Application

Detect Interleukin-10 using this Anti-Interleukin-10 Antibody validated for use in WB.

Quality

Evaluated by Western Blot in mouse Interleukin-10 recombinant protein.

Western Blot Analysis: 0.01 µg/mL of this antibody detected Interleukin-10 on 10 µg of mouse Interleukin-10 recombinant protein.

Target description

~18 kDa observed.

Analysis Note

Control
Mouse Interleukin-10 recombinant protein

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable