AB1592P
Anti-NMDAR2C Antibody, also recognizes NMDAR2A and 2B
Chemicon®, from rabbit
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
suitability
not suitable for immunohistochemistry
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... GRIN2C(2905)
Specificity
NMDAR2C. Immunolabels the 140 kD NMDAR2C subunit of the NMDA receptor. Also reacts with NMDAR2A and NMDAR2B by Western blot (180 kD).
Immunogen
Epitope: N-terminus
N-Terminal Fusion Protein of the NMDAR2C
Application
Detect NMDAR2C using this Anti-NMDAR2C Antibody, also recognizes NMDAR2A & 2B validated for use in IP & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Western blotting 1:100-1:200
Immunoprecipitation: 3 μL will (under the appropriate conditions) quantitatively immunoprecipitate all NMDAR2C in 200 μg of rat cerebellum.
Not recommended for use in immunohistochemistry since the antibody also reacts with NMDAR2A and NMDAR2B.
Optimal working dilutions must be determined by the end user.
Immunoprecipitation: 3 μL will (under the appropriate conditions) quantitatively immunoprecipitate all NMDAR2C in 200 μg of rat cerebellum.
Not recommended for use in immunohistochemistry since the antibody also reacts with NMDAR2A and NMDAR2B.
Optimal working dilutions must be determined by the end user.
Physical form
Affinity purified immunoglobulin. Lyophilized from ammonium bicarbonate (5 mM), some residual salt may be present. Reconstitute with 50 μL of PBS.
Storage and Stability
Maintain lyophilized antibody at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to six months.
Avoid repeated freeze/thaw cycles.
Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Spinal NMDA receptor phosphorylation correlates with the presence of neuropathic signs following peripheral nerve injury in the rat.
Camilla Ultenius, Bengt Linderoth, Bjorn A Meyerson, Johan Wallin
Neuroscience Letters null
Ionotropic glutamate receptors trigger microvesicle-mediated exocytosis of L-glutamate in rat pinealocytes.
S Yatsushiro, H Yamada, M Hayashi, A Yamamoto, Y Moriyama, S Yatsushiro, H Yamada et al.
Journal of Neurochemistry null
Josette S Lindahl et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 29(11), 2065-2073 (2004-05-13)
Phencyclidine (PCP) is a noncompetitive antagonist of the N-methyl-D-aspartate (NMDA) glutamate receptor subtype. It produces transient psychoses in normal individuals and exacerbates psychoses in schizophrenics. When administered to rodents, PCP elicits stereotypic behaviors including unrelenting head swaying, hyperlocomotion, and social
K K Yung
Neuroreport, 9(7), 1639-1644 (1998-06-19)
Immunocytochemical localization of metabotropic glutamate receptors (mGluRs) and ionotropic glutamate receptors (NMDA-type: NMDAR1 and NMDAR2A-C; AMPA-type: GluR1-4) was performed on sections of rat dorsal horn. Immunoreactivity for mGluR1 alpha was detected in laminae I-III of the dorsal horn, whilst mGluR2/3
H Wang et al.
Neuroscience, 188, 168-181 (2011-05-21)
Untimely activation of nicotinic acetylcholine receptors (nAChRs) by nicotine results in short- and long-term consequences on learning and behavior. In this study, the aim was to determine how prenatal nicotine exposure affects components of glutamatergic signaling in the hippocampus during
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