Skip to Content
Merck
All Photos(1)

Key Documents

AB1569

Sigma-Aldrich

Anti-Dopa Decarboxylase Antibody

Chemicon®, from rabbit

Synonym(s):

Anti-AADC

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

canine, bovine, rat, guinea pig, human, sheep

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NM_000790.3
NM_001082971.1

UniProt accession no.

P20711

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... CDNF(441549)

Specificity

DOPA Decarboxylase (DDC). Reacts with a single band of ~55 kDa by Western blot.

Immunogen

Recombinant bovine DDC expressed in E. coli and purified from inclusion bodies.

Application

Detect Dopa Decarboxylase using this Anti-Dopa Decarboxylase Antibody validated for use in IH & WB.
Immunoblotting: 1:500-1:1,000

Immunohistochemistry using formaldehyde-fixed brain sections.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Neuronal & Glial Markers

Physical form

Affinity purified immunoglobulin. Liquid in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.

Storage and Stability

Maintain at -20 to -80°C in undiluted aliquots for up to six months after date of receipt. Store in a NON-self-defrosting freezer. Avoid repeated freeze-thaw cycles.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Lack of regulation of aromatic L-amino acid decarboxylase in intact bovine chromaffin cells.
Jack C Waymire, John W Haycock
Journal of Neurochemistry null
Branden J Stansley et al.
Neuropharmacology, 67, 243-251 (2012-12-01)
L-dopa is a precursor for dopamine synthesis and a mainstay treatment for Parkinson's disease. However, l-dopa therapy is not without side effects that may be attributed to non-dopaminergic mechanisms. Synthesized dopamine can be neurotoxic through its enzymatic degradation by monoamine
Increased expression of VMAT2 in dopaminergic neurons during nicotine withdrawal.
Anne-Marie Duchemin,Hailing Zhang,Norton H Neff,Maria Hadjiconstantinou
Neuroscience Letters null
Innate immunity in insects: surface-associated dopa decarboxylase-dependent pathways regulate phagocytosis, nodulation and melanization in medfly haemocytes.
Sideri, M; Tsakas, S; Markoutsa, E; Lampropoulou, M; Marmaras, VJ
Immunology null
Jennifer M King et al.
Life sciences, 89(17-18), 638-643 (2011-08-30)
l-3,4-Dihydroxyphenylalanine (L-DOPA) is the most effective symptomatic treatment for Parkinson's disease (PD), but PD patients usually experience a successful response to L-DOPA therapy followed by a progressive loss of response. L-DOPA efficacy relies on its decarboxylation by aromatic l-amino acid
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service