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form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
color
clear yellow
shipped in
dry ice
storage temp.
−70°C
General description
Complement C3-depleted serum is a human serum that is depleted of complement component C3. It is prepared from serum that has been shown by certified tests to be negative for Hepatitis B surface antigen (HBsAg) and antibodies to hepatitis C virus (HCV), human immunodeficiency virus (HIV-I), and HIV-II.
Application
Complement C3-Depleted Serum, Human has been used to study its effects on the α-secretase activity of umbilical cord blood serum (CBS).
Packaging
Please refer to vial label for lot-specific concentration.
Warning
Toxicity: Standard Handling (A)
Unit Definition
Classical Pathway Activity: One C3H50 unit measured by classical pathway activation is defined as the amount of C3 required to yield 50% lysis of 3 x 10⁷ EA when incubated in the presence of the recommended volume of C3-Dpl for 30 min at 37°C in a total reaction volume of 500 µl GVB++.
Physical form
In 150 mM NaCl, 50 mM sodium phosphate, pH 7.2.
Preparation Note
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HCV, HIV-I, and HIV-II.
Reconstitution
Following initial thaw, aliquot and freeze (-70°C).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
12 - Non Combustible Liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Ahsan Habib et al.
Cell transplantation, 27(4), 666-676 (2018-06-07)
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