P-121

Prednisolone solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₂₁H₂₈O₅
• CAS Number: 50-24-8
• Molecular Weight: 360.44
• MDL number: MFCD00003649
• UNSPSC Code: 41116107
• PubChem Substance ID: 329820079
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in acetonitrile
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• InChI: 1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
• InChI key: OIGNJSKKLXVSLS-VWUMJDOOSA-N
• Gene Information: human ... NR3C1(2908)

Description

General description

Prednisolone is a synthetic glucocorticoid and derivative of cortisol which is used to treat a variety of inflammatory and auto-immune conditions. It is the active metabolite of the drug prednisone and is used especially in patients with liver failure, as these individuals are unable to metabolise prednisone into prednisolone. This Certified Spiking Solution^® is suitable for use as starting materials in the preparation of calibrators and controls for prednisolone testing methods by GC/MS or LC-MS/MS.

Application

• Casein hydrolysate as a rapid and/or enteric dissolving additive for oral drugs.: This study investigates the use of Prednisolone solution in formulating rapid and enteric dissolving oral drugs. It highlights the importance of Prednisolone liquid for biochemical assays and in vitro glucocorticoid studies, demonstrating its utility in pharmaceutical research applications (Imai et al., 1998).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302 + H312 + H332,H319
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 35.6 °F - closed cup
• Flash Point(C): 2.0 °C - closed cup