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LM4000

Avanti

19:0 Cholesterol ester

Avanti Polar Lipids LM4000, (methanol/chloroform/toluene (50:25:25) solution)

Synonym(s):

cholest-5-en-3β-yl nonadecanoate

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About This Item

Empirical Formula (Hill Notation):
C46H82O2
CAS Number:
25605-90-7
Molecular Weight:
667.14
UNSPSC Code:
12352211
NACRES:
NA.25

form

(methanol/chloroform/toluene (50:25:25) solution)

packaging

pkg of 1 × 1 mL (LM4000-1EA)

manufacturer/tradename

Avanti Polar Lipids LM4000

concentration

~10 μg/mL (Refer to C of A for lot specific concentration.)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@]12[C@]([C@](CC[C@H](OC(CCCCCCCCCCCCCCCCCC)=O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC(C)C

General description

19:0 Cholesterol ester is the central core of lipoprotein particles. CE formation is catalyzed by the enzyme lecithin cholesterol acyl transferase (LCAT).

Application

19:0 Cholesterol ester has been used as a quantitative lipid standard to monitor different lipid extract concentrations.

Biochem/physiol Actions

CE hydrolysis mediates reverse cholesterol transport in macrophage foam cells.

Packaging

2 mL Amber Glass Sealed Ampule (LM4000-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Asp. Tox. 1 - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT RE 2 - STOT SE 1 - STOT SE 3

Target Organs

Central nervous system, Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mammalian acyl-CoA:cholesterol acyltransferases
Buhman KF, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1529(1), 142-154 (2000)
The critical role of neutral cholesterol ester hydrolase 1 in cholesterol removal from human macrophages.
Igarashi M, et al.
Circulation Research, 107(11), 1387-1395 (2010)
A comprehensive method for lipid profiling by liquid chromatography-ion cyclotron resonance mass spectrometry
Fauland A, et al.
Journal of Lipid Research, 52(12), 2314-2322 (2011)

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