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810330C

Avanti

18:1 Dansyl PE

Avanti Polar Lipids 810330C

Synonym(s):

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(5-dimethylamino-1-naphthalenesulfonyl) (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C53H92N3O10PS
CAS Number:
Molecular Weight:
994.35
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810330C-1mg)
pkg of 5 × 1 mL (810330C-5mg)

manufacturer/tradename

Avanti Polar Lipids 810330C

concentration

1 mg/mL (810330C-1mg)
1 mg/mL (810330C-5mg)

shipped in

dry ice

storage temp.

−20°C

General description

Phosphoethanolamine (PHOS) is a precursor to phosphatidylcholine and phosphatidylethanolamine. 18:1 Dansyl PE is a hygroscopic, light sensitive lipid.

Application

18:1 Dansyl PE has been used in unilamellar liposome preparation. It may be used to incorporate into liposomes as the fluorescence energy transfer (FRET) acceptor. It may also be used as a component in Golgi-like acceptor liposomes for lipid transfer assay.

Biochem/physiol Actions

Phosphatidylethanolamine controls membrane fluidity in eukaryotic cells. Phosphoethanolamine (PHOS) has the ability to repress tumour growth both in vitro and in vivo. It possesses anticarcinogenic effects. It can also prevent the mRNA expression of cyclin D1 and VEGFR1 (vascular endothelial growth factor receptor 1).

Packaging

5 mL Amber Glass Screw Cap Vial (810330C-1mg)
5 mL Amber Glass Screw Cap Vial (810330C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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INAUGURAL ARTICLE by a Recently Elected Academy Member: Resistin-like molecule β is a bactericidal protein that promotes spatial segregation of the microbiota and the colonic epithelium.
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Proceedings of the National Academy of Sciences of the USA, 114(42), 11027-11027 (2017)
Interaction of human chloride intracellular channel protein 1 (CLIC1) with lipid bilayers: a fluorescence study
Hare JE, et al.
Biochemistry, 55(27), 3825-3833 (2016)
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Biochemical and biophysical research communications, 521(3), 732-738 (2019-11-11)
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Synthetic phosphoethanolamine: the state of the art of scientific production
Anastacio L de B, et al.
Brazilian Journal of Pharmaceutical Sciences, 53(4), 3658-3667 (2017)
The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution
Sobajima T, et al.
The Journal of Cell Biology, 217(5), 1777-1796 (2018)

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