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KITALYSIS-CUCN

Sigma-Aldrich

KitAlysis High-Throughput Copper C-N Cross-Coupling Reaction Screening Kit-Pack of 2

Synonym(s):

Copper Catalyzed C-N Coupling Kit

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.22

reaction suitability

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings

Application

Screening kit for Copper C-N Cross-Coupling Reactions. Step-by-step user guides and a downloadable experimental excel sheets are provided in the below hyperlinks.

Step-by-Step Guide for KitAlysis High-Throughput Copper C-N Cross-Coupling Reaction Screening Kit

Downloadable experimental excel sheet

Each kit contains 2 customizable screening sets that include the following components:
  • 24 (6 x 4) pre-weighed ligands in glass vials loaded with stir bars, topped with cap mat
  • Potassium phosphate: 4 pre-weighed vials with product labels and lids
  • CuI (soluble source) in preweighed vial
  • 4 degassed anhydrous solvents (dioxane, DMAc, toluene, and DMSO) in ampules
  • 1 internal standard
  • 2 KitAlysis 24-Well reaction block replacement films
  • 8 stir bars for stock solutions
  • Ampule cracker

Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Features and Benefits

  • Designed and tested by synthetic chemists.
  • Easily run 24-microscale reaction in parallel.
  • Suggested conditions: 10 μmol reactions with 1 μmol catalyst (10 mol%) 0.1 M concentration, and 3 equiv. base.
  • Customizable and downloadable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.

Legal Information

KitAlysis is a trademark of Sigma-Aldrich Co. LLC

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Carc. 1B - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

Flash Point(F)

39.2 °F

Flash Point(C)

4 °C


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Articles

KitAlysis High-Throughput Screening Kits provide solution to efficiently identify or optimize suitable catalytic reaction conditions. Chemist can rapidly run 24 unique micro scale reactions in parallel with tailored conditions.

Materials included in your KITALYSIS-CUCN-2PK High-Throughput Screening Kit

Protocols

KitAlysis™ Cu C-N (Buchwald-Hartwig) cross-coupling high-throughput screening kit. Detailed Set-Up User Guide and a downloadable excel file for calculations.

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