Skip to Content
Merck
All Photos(1)

Key Documents

More Documents

708496

Sigma-Aldrich

Acetyl chloride solution

1 M in methylene chloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C2H3ClO
CAS Number:
75-36-5
Molecular Weight:
78.50
MDL number:
MFCD00000719
UNSPSC Code:
12352101
PubChem Substance ID:
329762802
NACRES:
NA.22

form

liquid

Quality Level

100

concentration

1 M in methylene chloride

refractive index

n20/D 1.423

density

1.294 g/mL at 25 °C

SMILES string

CC(Cl)=O

InChI

1S/C2H3ClO/c1-2(3)4/h1H3

InChI key

WETWJCDKMRHUPV-UHFFFAOYSA-N

Related Categories

Application

Acetyl chloride (AcCl) can be used as:
  • An acylating reagent to prepare useful key intermediates in organic synthesis.
  • A reagent to convert oxathioacetals and dithioacetals into corresponding carbonyl compounds in the presence of sodium nitrite.
  • An activating or acylating reagent in solid-phase organic synthesis.
  • A reagent to prepare various alkyl and aryl tetrahydropyranyl ethers from corresponding alcohols.

Signal Word

Danger

Hazard Statements

H225 - H314 - H336 - H351

Hazard Classifications

Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

EUH014 - EUH071

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

39.9 °F

Flash Point(C)

4.4 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

Triethylamine ≥99%

Sigma-Aldrich

T0886

Triethylamine

A highly efficient procedure for regeneration of carbonyl groups from their corresponding oxathioacetals and dithioacetals using sodium nitrite and acetyl chloride in dichloromethane
Khan AT, et al.
Synlett, 2003(03), 0377-0381 (2003)
New phenylfluorenyl based linkers for solid phase synthesis
Bleicher KH, et al.
Tetrahedron Letters, 41(47), 9037-9042 (2000)
Peter C Papageorgiou et al.
Journal of hypertension, 32(7), 1523-1533 (2014-04-16)
Activated coagulation Factor XII (FXIIa) infusion increases peripheral resistance (TPR) and mean arterial pressure (MAP) of Brown Norway but not plasma kininogen deficient Brown Norway Katholiek (BNK) rats. FXIIa concentrations are elevated in hypertensive end-stage renal disease patients receiving conventional
Paolo Gelosa et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 34(6), 979-988 (2014-03-20)
The ADP-responsive P2Y12 receptor is expressed on both platelets and microglia. Clinical data show that ticagrelor, a direct-acting, reversibly binding P2Y12-receptor antagonist, reduces total cardiovascular events, including stroke. In our present study, we investigated the expression of P2Y12 receptors and
Silvie Van den Hoecke et al.
BMC genomics, 16, 79-79 (2015-03-12)
Influenza viruses exist as a large group of closely related viral genomes, also called quasispecies. The composition of this influenza viral quasispecies can be determined by an accurate and sensitive sequencing technique and data analysis pipeline. We compared the suitability
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service