471933

4-Iodophenylboronic acid

≥95.0%

• Synonym(s): B-(4-iodophenyl)-boronic acid, p-Iodophenylboronic acid, p-iodo-benzeneboronic acid
• Linear Formula: IC₆H₄B(OH)₂
• CAS Number: 5122-99-6
• Molecular Weight: 247.83
• MDL number: MFCD01319014
• UNSPSC Code: 12352103
• PubChem Substance ID: 24870773
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: ≥95.0%
• mp: 326-330 °C (lit.)
• SMILES string: OB(O)c1ccc(I)cc1
• InChI: 1S/C6H6BIO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4,9-10H
• InChI key: PELJYVULHLKXFF-UHFFFAOYSA-N

Description

Application

Reagent used for

• Copper-mediated ligandless aerobic fluoroalkylation
• Palladium-catalyzed aerobic oxidative cross-coupling reactions
• Recyclable magnetic-nanoparticle-supported palladium catalyst for the Suzuki coupling reactions
• Oxidative hydroxylation using a copper (Cu) catalyst
• Ligand-free palladium-catalyzed Suzuki-Miyaura cross-coupling
• Homocoupling using gold salts as a catalyst
• Ruthenium (Ru)-catalyzed cross-coupling
• CuI-catalyzed Suzuki coupling reactions
• Palladium-catalyzed domino Heck-Mizoroki/Suzuki-Miyaura reactions
• Manganese triacetate-mediated radical additions of arylboronic acids to alkenes

Reagent used in Preparation of

• Pleuromutilin derivatives for ribosomal binding and antibacterial activity via "Click Chemistry"
• Liquid crystalline polyacetylene derivatives

Other Notes

Contains varying amounts of anhydride

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves