253421
3-(2-Iodoacetamido)-PROXYL
free radical
Synonym(s):
3-(2-Iodoacetamido)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy, free radical
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About This Item
Empirical Formula (Hill Notation):
C10H18IN2O2
CAS Number:
Molecular Weight:
325.17
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.22
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form
solid
mp
162-164 °C (lit.)
functional group
amide
iodo
storage temp.
2-8°C
SMILES string
CC1(C)CC(NC(=O)CI)C(C)(C)N1[O]
InChI
1S/C10H18IN2O2/c1-9(2)5-7(12-8(14)6-11)10(3,4)13(9)15/h7H,5-6H2,1-4H3,(H,12,14)
InChI key
OQIGMSGDHDTSFA-UHFFFAOYSA-N
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General description
3-(2-Iodoacetamido)-PROXYL is a free radical used as a spin probe in spin labeling techniques. This technique is helpful in investigating the dynamic aspects of molecular interactions of substances, proteins, lipids, and cell membranes.
Application
Sulfhydryl group specific spin label. Applications include study of ozone-treated human and bovine erythrocyte membrane proteins and the orientation of myosin subfragment on muscle fibers. DNA fragments containing phosphorothioate diesters can be labeled by spin labels.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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