SRP2113

TFIIE, α (p56), α subunit, GST tagged human

recombinant, expressed in E. coli, ≥80% (SDS-PAGE)

• Synonym(s): FE, TF2E1, TFIIE-A
• UNSPSC Code: 12352202
• NACRES: NA.26

Properties

• biological source: human
• recombinant: expressed in E. coli
• Assay: ≥80% (SDS-PAGE)
• form: frozen liquid
• mol wt: ~76.2 kDa
• packaging: pkg of 10 μg
• storage condition: avoid repeated freeze/thaw cycles
• concentration: 450 μg/mL
• color: clear colorless
• NCBI accession no.: NM_005513
• UniProt accession no.: P29083
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... GTF2E1(2960)

Description

Biochem/physiol Actions

The human Transcription Factor IIE (TFIIE) is composed of 56 kDa and 34 kDa subunits and is shown to be a heterotetramer. The 56- kDa subunit contains a region similar to a zinc-binding domain and a region sharing homology with the catalytic loop of a kinase domain. TFIIE binds to RNA polymerase II in solution and joins the preinitiation complex probably concomitant with RNA polymerase II and TFIIF.

Physical form

Clear and colorless frozen liquid solution

Preparation Note

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable