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P3543

Sigma-Aldrich

Poly-L-lysine–FITC Labeled

mol wt 15,000-30,000

Synonym(s):

Fluorescein Labeled Poly-L-Lysine

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About This Item

MDL number:
MFCD00165427
UNSPSC Code:
12352209
NACRES:
NA.26

form

powder

mol wt

precursor poly-L-lysine • HBr 15,000-30,000
 15,000-30,000

extent of labeling

0.003-0.01 mol FITC per mol lysine monomer

color

yellow to orange

storage temp.

−20°C

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Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Vitreous is a barrier in nonviral gene transfer by cationic lipids and polymers.
Pitkanen L, Ruponen M, et al.
Pharmacological Research, 20, 576-583 (2003)
Marjo Männistö et al.
The journal of gene medicine, 7(4), 466-476 (2004-12-25)
Retinal pigment epithelium (RPE) maintains the function of photoreceptors and eyesight and is an important target for gene delivery. Since in some diseases RPE cells proliferate uncontrollably, we investigated the role of cell cycle in non-viral gene delivery into a
Larry J Millet et al.
Lab on a chip, 10(12), 1525-1535 (2010-04-15)
Wiring the nervous system relies on the interplay of intrinsic and extrinsic signaling molecules that control neurite extension, neuronal polarity, process maturation and experience-dependent refinement. Extrinsic signals establish and enrich neuron-neuron interactions during development. Understanding how such extrinsic cues direct
Leena Pitkänen et al.
The AAPS journal, 6(3), e25-e25 (2005-03-12)
We investigated the permeation of liposomal and polymeric gene delivery systems through neural retina into retinal pigment epithelium (RPE) and determined the roles of various factors in permeation and subsequent uptake of the delivery systems by RPE. Anterior parts and

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Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

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