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M6013

Sigma-Aldrich

Medroxyprogesterone

Synonym(s):

17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione, 17α-Hydroxy-6α-methylprogesterone, 6α-Methyl-5-pregnen-17α-ol-3,20-dione, 6-Dihydromegestrol

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About This Item

Empirical Formula (Hill Notation):
C22H32O3
CAS Number:
520-85-4
Molecular Weight:
344.49
Beilstein:
2510965
EC Number:
208-298-6
MDL number:
MFCD00069474
UNSPSC Code:
51111800
PubChem Substance ID:
24897065
NACRES:
NA.77

biological source

synthetic (organic)

Assay

≥98% (HPLC)

form

powder

solubility

chloroform: 50 mg/mL, clear, colorless to faintly yellow

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(C)=O

InChI

1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1

InChI key

FRQMUZJSZHZSGN-HBNHAYAOSA-N

Gene Information

rat ... Ar(24208)

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Caution

Much of the pharmacology literature refers to medroxyprogesterone acetate as medroxyprogesterone, but they are of course not the same substance.

related product

Product No.
Description
Pricing

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H361fd

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M F Martinez et al.
Reproduction in domestic animals = Zuchthygiene, 47(2), 230-237 (2011-09-03)
Two experiments were designed to investigate the administration of intravaginal progesterone in protocols for oestrus and ovulation synchronization in beef heifers. In Experiment 1, cyclic Black Angus heifers (n = 20) received an Ovsynch protocol and were randomly assigned to
Carolyn J Crandall et al.
Breast cancer research and treatment, 132(1), 275-285 (2011-11-02)
The associations between breast tenderness during use of conjugated equine estrogen (CEE) therapy with or without medroxyprogesterone (MPA) therapy and subsequent breast cancer risk are unknown. We analyzed data from the Women's Health Initiative Estrogen plus Progestin (N = 16,608
D R Reilly et al.
Canadian journal of psychiatry. Revue canadienne de psychiatrie, 45(6), 559-563 (2000-09-15)
To propose a protocol for minimizing medical complications associated with the use of cyproterone, medroxyprogesterone, and depot leuprolide to treat paraphilia. Review of the relevant literature. Certain patient populations should not be treated with these medications, and medical complications associated
Toshio Hayashi et al.
Nitric oxide : biology and chemistry, 24(4), 199-203 (2011-04-26)
A comparison between the atheroprotective and osteoprotective effects of the selective estrogen receptor modulator (SERM) raloxifene and those of hormone replacement therapy (HRT) has not been made in elderly women. A randomized prospective controlled trial was performed in a cohort
The role of medroxyprogesterone acetate (MPA) in the treatment of renal adenocarcinoma.
M Kjaer
Cancer treatment reviews, 15(3), 195-209 (1988-09-01)
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