J4252

JWH-015

≥98% (HPLC), powder

• Synonym(s): (2-Methyl-1-propyl-1H-indol-3-yl)-1-naphthalenylmethanone
• Empirical Formula (Hill Notation): C₂₃H₂₁NO
• CAS Number: 155471-08-2
• Molecular Weight: 327.42
• MDL number: MFCD02094630
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278502
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• drug control: regulated under CDSA - not available from Sigma-Aldrich Canada
• color: off-white
• solubility: DMSO: >20 mg/mL (with heating)
• storage temp.: −20°C
• SMILES string: CCCn1c(C)c(C(=O)c2cccc3ccccc23)c4ccccc14
• InChI: 1S/C23H21NO/c1-3-15-24-16(2)22(20-12-6-7-14-21(20)24)23(25)19-13-8-10-17-9-4-5-11-18(17)19/h4-14H,3,15H2,1-2H3
• InChI key: LJSBBBWQTLXQEN-UHFFFAOYSA-N
• Gene Information: human ... CNR2(1269) ; rat ... Cnr1(25248)

Description

Application

JWH-015 has been used to study its effect on tumor-evoked pain behavior. It has also been used to study its protective effects on rat brain mitochondria upon paraquat exposure.

Biochem/physiol Actions

JWH-015 is a selective CB2 cannabinoid receptor agonist. JWH-015 is structurally classified as naphthoylindoles.

Features and Benefits

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves