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HT501640

Sigma-Aldrich

Formalin solution, neutral buffered, 10%

histological tissue fixative

Synonym(s):

Formaldehyde, Methanal

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About This Item

MDL number:
MFCD00003274
UNSPSC Code:
12352114
PubChem Substance ID:
24895891
NACRES:
NA.47

concentration

10% formalin (approx. 4% formaldehyde)

color

colorless

pH

6.90-7.10

density

1.080 g/cm3

application(s)

hematology
histology

storage temp.

room temp

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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General description

Formalin solution, neutral buffered, 10% is the most commonly used fixative for light microscopy. It requires a relatively short period of fixation. It is suitable for the long-term storage of tissue. Once properly fixed, the tissue should be able to withstand the subsequent stages of tissue processing or staining. 10% NBF is well suited for large throughput laboratories, and requires a relatively short period of fixation, but can also be used for the long-term storage of tissue. Formalin fixation is thought to form between the aldehydes and the proteins, creating a gel, thus retaining cellular constituents in their in vivo relationship.

Application

Formalin solution, neutral buffered, 10% has been used as a popular general purpose histological fixative.It helps to preserve tissue samples by preventing decay and maintaining their molecular integrity.
Popular general purpose histological fixative.

Packaging

Item is packaged in a 20 L Cubitainer consisting of a plastic bladder inside of a cardboard box with an attached spigot.

Physical form

Neutral buffered solution

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Skin Sens. 1

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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