54880

3-Hydroxybenzylhydrazine dihydrochloride

≥98.0% (HPLC)

• Synonym(s): α-Hydrazino-m-cresol dihydrochloride, 3-(Hydrazinomethyl)phenol dihydrochloride, NSD-1015
• Linear Formula: HOC₆H₄CH₂NHNH₂ · 2HCl
• CAS Number: 81012-99-9
• Molecular Weight: 211.09
• Beilstein: 9282965
• EC Number: 279-659-3
• MDL number: MFCD00044695
• UNSPSC Code: 12352202
• PubChem Substance ID: 24878937
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98.0% (HPLC)
• form: solid
• mp: 137-140 °C; 138-140 °C (lit.)
• solubility: H₂O: 50 mg/mL, slightly hazy, faintly yellow
• SMILES string: Cl[H].Cl[H].NNCc1cccc(O)c1
• InChI: 1S/C7H10N2O.2ClH/c8-9-5-6-2-1-3-7(10)4-6;;/h1-4,9-10H,5,8H2;2*1H
• InChI key: ONOJPUDFIOEGCX-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Inhibitor of L-aromatic amino acid decarboxylase; crosses blood brain barrier.

Inhibitor of L-aromatic amino acid decarboxylase; crosses blood brain barrier. Also inhibits GABA aminotransferase, as well as other pyridoxal-phosphate-requiring enzymes, by forming the 3-hydroxybenzylhydrazone of that cofactor.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H315,H318,H335
• Precautionary Statements: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves