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P0380

Sigma-Aldrich

L-Proline

≥99% (HPLC), ReagentPlus®

Synonym(s):

(S)-Pyrrolidine-2-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C5H9NO2
CAS Number:
147-85-3
Molecular Weight:
115.13
Beilstein:
80810
EC Number:
205-702-2
MDL number:
MFCD00064318
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24898097
NACRES:
NA.26

product name

L-Proline, ReagentPlus®, ≥99% (HPLC)

Quality Level

200

product line

ReagentPlus®

Assay

≥99% (HPLC)

form

powder

impurities

L-Hydroxyproline, free

color

white

mp

228 °C (dec.) (lit.)

application(s)

detection

SMILES string

OC(=O)[C@@H]1CCCN1

InChI

1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1

InChI key

ONIBWKKTOPOVIA-BYPYZUCNSA-N

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Application

L-Proline has been used:
  • As a supplement during the preparation of chondrogenic medium and synthetic dextrose minimal medium (SD).
  • As a standard during the identification of metabolites in serum samples.
  • In a study to prepare L-proline-L-phenylalanine (L-Pro-L-Phe) mixture in aqueous acetonitrile.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCL3643
SLCH4834
SLCG4938
SLCD1522
SLBZ8461

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Natasja Leth Joergensen et al.
BioResearch open access, 4(1), 109-114 (2015-08-27)
Cartilage regeneration is a fast growing field that combines biotechnology and molecular techniques in creating new tissue mimicking the native microenvironment. Human embryonic stem cells (hESCs) are a highly potent cell source for cartilage regeneration owing to their infinite proliferation
Quantification of extracellular ammonium concentrations and transporter activity in yeast using AmTrac fluorescent sensors.
Ast C, et al.
Bio-protocol, 5, e1372-e1372 (2015)
Proline: a multifunctional amino acid
La' szlo' Szabados and Arnould Savoure
Trends in Plant Science, 1-9 (2009)
Mieczysław Sajewicz et al.
Journal of chromatographic science, 53(1), 31-37 (2014-03-05)
We employ the achiral liquid chromatography with diode array, evaporative light scattering and mass spectrometric detection (HPLC-DAD, HPLC-ELSD and LC-MS) to assess structural instability (understood as spontaneous oscillatory chiral conversion and spontaneous oscillatory condensation) of the two pairs of amino
Proline-Dependent Structural and Biological Properties of Peptides and Proteins
Arieh Yaron
Critical Reviews in Biochemistry and Molecular Biology, 28, 31-81 (2008)
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