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H4784

Sigma-Aldrich

Heparin sodium salt from porcine intestinal mucosa

≥180 USP units/mg

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About This Item

CAS Number:
9041-08-1
MDL number:
MFCD00081689
UNSPSC Code:
12352201
NACRES:
NA.21

biological source

Porcine intestinal mucosa

Quality Level

200

form

powder

specific activity

≥180 USP units/mg

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow

cation traces

Ca: ≤20 ppm

storage temp.

2-8°C

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General description

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Quality

Low calcium content

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCC4685
SLBQ1351V
SLBP3704V
SLBN0543V
SLBF3813V

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Linda Cruz et al.
PloS one, 8(7), e68379-e68379 (2013-07-19)
Human papillomavirus (HPV) infection is the leading cause of cervical cancer world-wide. Here, we show that native HPV particles produced in a differentiated epithelium have developed different strategies to infect the host. Using biochemical inhibition assays and glycosaminoglycan (GAG)-negative cells
Eve Draper et al.
PloS one, 8(5), e61825-e61825 (2013-05-08)
The current generation of Human Papillomavirus (HPV) vaccines, Cervarix® and Gardasil®, exhibit a high degree of efficacy in clinical trials against the two high-risk (HR) genotypes represented in the vaccines (HPV16 and HPV18). High levels of neutralizing antibodies are elicited
Felix J Hartmann et al.
Cell reports, 28(3), 819-831 (2019-07-18)
The success of immunotherapy has led to a myriad of clinical trials accompanied by efforts to gain mechanistic insight and identify predictive signatures for personalization. However, many immune monitoring technologies face investigator bias, missing unanticipated cellular responses in limited clinical
Sara L Bissett et al.
Scientific reports, 6, 39730-39730 (2016-12-23)
The human papillomavirus (HPV) vaccines consist of major capsid protein (L1) virus-like particles (VLP) and are highly efficacious against the development of cervical cancer precursors attributable to oncogenic genotypes, HPV16 and HPV18. A degree of vaccine-induced cross-protection has also been
William H Thiel et al.
PloS one, 7(9), e43836-e43836 (2012-09-11)
The broad applicability of RNA aptamers as cell-specific delivery tools for therapeutic reagents depends on the ability to identify aptamer sequences that selectively access the cytoplasm of distinct cell types. Towards this end, we have developed a novel approach that
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