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Key Documents

27714

Sigma-Aldrich

L-(+)-Lactic acid solution

meets analytical specification of Ph. Eur., BP, 88-92% total acid basis

Synonym(s):

(S)-2-Hydroxypropionic acid, Sarcolactic acid

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About This Item

Empirical Formula (Hill Notation):
C3H6O3
CAS Number:
Molecular Weight:
90.08
Beilstein:
1720251
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

Quality Level

Assay

88-92% total acid basis

quality

meets analytical specification of Ph. Eur., BP

impurities

insoluble in ether, complies
methanol, complies (GC)
residual solvents, complies
sugar and orther red. Substances, complies
≤0.0005% heavy metals (as Pb)

ign. residue

≤0.05% (as SO4)

solubility

water: soluble(lit.)

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg

cation traces

Ca: ≤100 mg/kg
Fe: ≤10 mg/kg

suitability

complies for appearance of solution

functional group

carboxylic acid
hydroxyl

SMILES string

C[C@H](O)C(O)=O

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1

InChI key

JVTAAEKCZFNVCJ-REOHCLBHSA-N

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Application

  • Pharmaceutical formulations: Research on in-situ forming PLGA implants highlights the use of L-(+)-Lactic acid solution as a solvent to reduce toxicity, underlining its critical function in pharmaceutical development and safer drug delivery systems (Ramos et al., 2024).

Other Notes

Aqueous solutions of l(+)-Lactate.
The article number 27714-4X2.5L will be discontinued. Please order the single bottle 27714-2.5L which is physically identical with the same exact specifications.
The article number 27714-6X1L will be discontinued. Please order the single bottle 27714-1L which is physically identical with the same exact specifications.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1C

Supplementary Hazards

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

230.0 °F

Flash Point(C)

110 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

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Swelling and hydrolytic degradation of poly (D, L-lactic acid) in aqueous solutions.
Proikakis C S, et al.
Polymer Degradation and Stability, 91(3), 614-619 (2006)
Ayşe Ezgi Ünlü
Waste and biomass valorization, 1-18 (2021-03-18)
Olive leaf as an agricultural waste contains valuable bioactive compounds that are mainly used for pharmaceutical and cosmetic industries. Lately the major component, oleuropein, has gained extra attention due to the anti-viral activity against SARS-CoV-2 that causes Coronavirus disease (Covid-19).
Synthesis and characterization of pH-sensitive hydrogels based on chitosan and D, L-lactic acid.
Qu X, et al.
Journal of Applied Polymer Science, 74(13), 3193-3202 (1999)
Recovery of L-(+)-lactic acid by anion exchange resin Amberlite IRA-400.
Cao X, et al.
Biochemical Engineering Journal, 11(2), 189-196 (2002)
Joshua I Raji et al.
Current biology : CB, 29(8), 1253-1262 (2019-04-02)
Mosquitoes use olfaction as a primary means of detecting their hosts. Previously, the functional ablation of a family of Aedes aegypti olfactory receptors, the odorant receptors (ORs), was not sufficient to reduce host seeking in the presence of carbon dioxide

Protocols

Separation of L-(+)-Lactic acid, analytical standard; D-(−)-Lactic acid, 93-107%

Chromatograms

application for HPLC

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