2106
Heparin sodium salt from porcine intestinal mucosa
endotoxin, free
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About This Item
biological source
Porcine intestinal mucosa
Quality Level
form
powder
usage
sufficient for 5 mL blood anticoagulant
packaging
preweighed vial of 300 USP units
impurities
endotoxin, free
color
beige
solubility
water: soluble 50 g/L
acetone: insoluble
alcohol: insoluble
benzene: insoluble
chloroform: insoluble
diethyl ether: insoluble
compatibility
for use with E-Toxate™
storage temp.
room temp
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Application
Heparin sodium salt from porcine intestinal mucosa has been used as a M199 medium supplement used for maintaining human umbilical vein endothelial cells.
Biochem/physiol Actions
Heparin sodium salt is the salt form of heparinic acid and is a polymer classified as a mucopolysaccharide or a glycosoaminoglycan. It is an anticoagulant that produces its major anticoagulant effect by activating antithrombin. Heparin binds to antithrombin III, a naturally occurring plasma protease inhibitor and accelerates significantly the rate at which antithrombin III (AT-III) inhibits coagulation proteases (factor Xa and thrombin). Additionally, it also facilitates the stabilization and regulation of tryptase as an enzymatically active tetramer.
Caution
Not for injection.
Other Notes
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Legal Information
E-Toxate is a trademark of Sigma-Aldrich Co. LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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