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MAB1961F

Sigma-Aldrich

Anti-Integrin αVβ5 Antibody, clone P1F6, FITC conjugated

clone P1F6, Chemicon®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

conjugate

FITC conjugate

antibody form

purified antibody

antibody product type

primary antibodies

clone

P1F6, monoclonal

species reactivity

human, chicken

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable

isotype

IgG1

suitability

not suitable for immunohistochemistry (Paraffin)

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGAV(3685)

Application

Anti-Integrin αVβ5 Antibody, clone P1F6, FITC conjugated detects level of Integrin αVβ5 & has been published & validated for use in FC, IF, IH.
Flow cytometry

Optimal working dilutions must be determined by the end user.

Physical form

In buffer containing 0.02M PB pH 7.6, 0.25M NaCl, 0.1% NaN3 with 15mg/ml BSA as a stabilizer.

Storage and Stability

Store between 2 and 8°C in undiluted aliquots for up to 12 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Functional analysis of a recombinant PIII-SVMP, GST-acocostatin; an apoptotic inducer of HUVEC and HeLa, but not SK-Mel-28 cells.
Teklemariam, T; Seoane, AI; Ramos, CJ; Sanchez, EE; Lucena, SE; Perez, JC; Mandal, SA; Soto, JG
Toxicon null
Sara E Lucena et al.
Toxicon : official journal of the International Society on Toxinology, 60(1), 31-39 (2012-04-03)
Snake venom disintegrins inhibit platelet aggregation and have anti-cancer activities. In this study, we report the cloning, expression, and functional activities of a recombinant disintegrin, r-viridistatin 2 (GenBank ID: JQ071899), from the Prairie rattlesnake. r-Viridistatin 2 was tested for anti-invasive
Q Zhou et al.
Biochemical and biophysical research communications, 267(1), 350-355 (2000-01-07)
Contortrostatin is a homodimeric disintegrin from snake venom. We have shown that contortrostatin binds to integrins alphaIIbbeta3, alpha5beta1, and alphavbeta3. We now use several criteria to demonstrate the binding of contortrostatin to alphavbeta5. First, incubation of T24 cells, which express
Yang Zhang et al.
Oncology letters, 12(5), 3241-3249 (2016-12-03)
Lung cancer is the leading cause of cancer-associated mortality, worldwide. For this reason, novel therapies are required for the treatment of this devastating disease. Cetuximab is a monoclonal antibody against epidermal growth factor receptor (EGFR), which is overexpressed in a

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