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07-471

Sigma-Aldrich

Anti-Daxx Antibody

serum, Upstate®

Synonym(s):

Anti-BING2, Anti-DAP6, Anti-EAP1, Anti-SMIM40

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat, mouse, hamster

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_001350

UniProt accession no.

Q9UER7

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

hamster ... Daxx(101836409)
human ... DAXX(1616)
mouse ... Daxx(13163)
rat ... Daxx(140926)

Specificity

Daxx

Immunogen

GST fusion protein corresponding to residues 472-740 of human Daxx.

Application

Anti-Daxx Antibody is an antibody against Daxx for use in IP, WB & IC.

Quality

routinely evaluated by immunoblot in HeLa nuclear extract

Target description

110 kDa

Linkage

Replaces: 04-445

Analysis Note

Control
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes.
Schreiner, S; Burck, C; Glass, M; Groitl, P; Wimmer, P; Kinkley, S; Mund, A; Everett, RD; Dobner, T
Nucleic Acids Research null
SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes.
Cuchet-Lourenco, D; Boutell, C; Lukashchuk, V; Grant, K; Sykes, A; Murray, J; Orr, A; Everett, RD
PLoS Pathogens null
Roger D Everett
Journal of virology, 90(1), 167-179 (2015-10-16)
Intrinsic immunity is an aspect of antiviral defense that operates through diverse mechanisms at the intracellular level through a wide range of constitutively expressed cellular proteins. In the case of herpesviruses, intrinsic resistance involves the repression of viral gene expression
Friederike Neumann et al.
The Journal of general virology, 97(11), 2926-2938 (2016-09-02)
Merkel cell polyomavirus (MCPyV) is associated with Merkel cell carcinoma (MCC), a rare but aggressive skin cancer. The virus is highly prevalent: 60-80 % of adults are seropositive; however, cells permissive for MCPyV infection are unknown. Consequently, very little information about
Comparison of the biological and biochemical activities of several members of the alphaherpesvirus ICP0 family of proteins.
RD Everett, C Boutell, C McNair, L Grant, A Orr
Journal of virology null
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