G-018

Gabapentin-¹³C₃ solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₆¹³C₃H₁₇NO₂
• Molecular Weight: 174.21
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: (Snap-N-Spike^®)
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C

Description

General description

Sold under the trade names Neurontin^®, Nupentin, or Gabarone, gabapentin is an anticonvulsant drug used primarily for treatment of seizures, fibromyalgia, and neuropathic pain. This internal standard is suitable for mass spectrometry-based testing or isotope dilution methods of gabapentin in forensic analysis, clinical toxicology, pain prescription monitoring, or urine drug testing.

Application

<ul>
<li><strong>Pharmacokinetic studies with rapid LC-MS/MS methods:</strong> Gabapentin-¹³C3 is used for accurate measurement in therapeutic monitoring and pharmacokinetic studies, promoting better patient management in clinical pharmacology (Phillips et al., 2021).</li>
<li><strong>Comprehensive drug class analysis in blood samples:</strong> Techniques for the determination of multiple drug classes in whole blood via LC-MS/MS, including gabapentin, illustrate the critical role of stable isotope-labeled standards like Gabapentin-¹³C3 in enhancing analytical precision and reliability in toxicological and pharmacological research (J rgenrud et al., 2021).</li>
</ul>

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Neurontin is a registered trademark of Warner-Lambert Co.

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup