850524P

CHEMS

Avanti Polar Lipids

• Synonym(s): 3β-Hydroxy-5-cholestene 3-hemisuccinate; 5-Cholesten-3β-ol 3-hemisuccinate; CHS
• Empirical Formula (Hill Notation): C₃₁H₅₀O₄
• CAS Number: 1510-21-0
• Molecular Weight: 486.73
• UNSPSC Code: 12161902
• NACRES: NA.25

Properties

• description: cholesteryl hemisuccinate
• Assay: >99% (TLC)
• form: powder
• mol wt: 486.73 g/mol
• packaging: pkg of 1 × 1 g (850524P-1g); pkg of 1 × 5 g (850524P-5g)
• manufacturer/tradename: Avanti Polar Lipids
• technique(s): protein quantification: suitable
• application(s): cell analysis
• shipped in: dry ice
• storage temp.: −20°C
• InChI: 1S/C31H50O4/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(35-29(34)14-13-28(32)33)15-17-30(22,4)27(24)16-18-31(25,26)5/h9,20-21,23-27H,6-8,10-19H2,1-5H3,(H,32,33)/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1
• InChI key: WLNARFZDISHUGS-MIXBDBMTSA-N

Description

General description

Cholesteryl hemisuccinate (CHEMS) is an acidic cholesterol ester.

Application

CHEMS is suitable:

• to prepare multifunctional envelope-type nano device (MEND) by a lipid film hydration method based on electrostatic interactions
• to as a component in bolavesicle
• to prepare liposome (LS)
• for the preparation of anionic liposomes by the lipid thin film hydration and freeze/thaw technique and to encapsulate ovalbumin (OVA) and listeriolysin O (LLO)
• to prepare liposomal membranes to study its effect on the physical–chemical properties of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) liposomes

Biochem/physiol Actions

CHEMS can help to maintain the stability of dioleoylphosphatidylethanolamine (DOPE). This amphipathic lipid is used in mixtures with dioleoylphosphatidylethanolamine (DOPE) to form ′pH sensitive′ fusogenic vesicles. It can control cell growth.

Packaging

20 mL Clear Glass Screw Cap Vial (850524P-1g)

30 mL Amber Wide Mouth Glass Bottle with Screw Cap (850524P-5g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable