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JKA5101

Sigma-Aldrich

HS-PEG7500-COOH

average Mn 7,500

Synonym(s):

HS-PEG-COOH, Polyethylene glycol, Thiol-PEG-Carboxyl, HS-PEG-COOH

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About This Item

Linear Formula:
HS(CH2CH2O)nCH2COOH
UNSPSC Code:
12162002
NACRES:
NA.23

form

solid

mol wt

average Mn 7,500

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions
reactivity: amine reactive

reagent type: cross-linking reagent
reaction type: Polymerization Reactions
reactivity: thiol reactive

polymer architecture

shape: linear
functionality: heterobifunctional

General description

Product is a thiolated carboxylic-polyethylene . 4α;-sulfanyl—ω carboxy PEG (HS–PEG–COOH) heterobifunctional PEGs with functional end-groups of very different reactivity. HS-PEG-COOH inhibits nonspecific binding to living cells.

Application

HS-PEG-COOH may be tethered to the gold nanoparticle end during the fabrication of epidermal growth factor (EGF)-conjugated surface-enhanced Raman spectroscopy (SERS) nanoparticles. HS-PEG-COOH was coated onto silicon-on-insulator photonic biosensor chips. Quantum dots (QD)/ virus-like particles (VLPs) could be obtained only from HS-PEG-COOH-coated QDs. It may be used to stabilize nanoparticles and prevent its aggregation.
Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization

Legal Information

Product of JenKem Technology

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Tian, L., et al.
Biosensors And Bioelectronics, 59 (2014)
Nam, K., et al.
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Antibody-functionalized SERS tags with improved sensitivity.
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Chemical Communications (Cambridge, England), 47(31), 8784-8786 (2011)

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