D17408
1,7-Diaminoheptane
98%
Synonym(s):
1,7-Heptanediamine, Heptamethylenediamine
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About This Item
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Quality Level
Assay
98%
form
solid
bp
223-225 °C (lit.)
mp
26-29 °C (lit.)
SMILES string
NCCCCCCCN
InChI
1S/C7H18N2/c8-6-4-2-1-3-5-7-9/h1-9H2
InChI key
PWSKHLMYTZNYKO-UHFFFAOYSA-N
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General description
1,7-Diaminoheptane, also known as heptamethylenediamine, is an organic compound with two amine groups at opposite ends of a seven-carbon chain. It is widely used in organic synthesis as a building block in the production of polyamides and other polymers.
Application
- Novel Hydrogels for Biomedical Applications: Research on the synthesis and characterization of pH-responsive aminated alginate derivatives using 1,7-Diaminoheptane, targeting advancements in tissue engineering and drug delivery systems. This study showcases the utility of 1,7-Diaminoheptane in developing hydrogels that respond to pH changes, potentially enhancing cell growth and targeted drug release (Khodayar et al., 2023).
- Advanced Materials in Photoluminescence: Investigation into the properties of 1,7-Diaminoheptane in enhancing broadband photoluminescence in hybrid perovskites for optoelectronic applications. This research highlights its potential in developing new materials for efficient light emission technologies (Deng et al., 2020).
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point(F)
190.4 °F - closed cup
Flash Point(C)
88 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Bioorganic & medicinal chemistry, 6(3), 253-270 (1998-05-06)
Deoxyhypusine synthase catalyzes the first step in the posttranslational biosynthesis of the unusual amino acid hypusine [N epsilon-(4-amino-2-hydroxybutyl)lysine] in eukaryotic translation initiation factor 5A (eIF-5A). eIF-5A and its single hypusine residue are essential for cell proliferation. Two series of 1,7-diaminoheptane
Analytical chemistry, 65(6), 704-706 (1993-03-15)
Tumor cells contain much higher levels of common polyamines such as putrescine, spermidine, and spermine than normal cells. Our previous work demonstrated that high-performance capillary zone electrophoresis with indirect photometric detection was suitable for the determination of underivatized free polyamines
Biomolecules, 10(3) (2020-03-12)
The biogenic polyamines, spermine, spermidine (Spd) and putrescine (Put) are present at micro-millimolar concentrations in eukaryotic and prokaryotic cells (many prokaryotes have no spermine), participating in the regulation of cellular proliferation and differentiation. In mammalian cells Put is formed exclusively
Foods (Basel, Switzerland), 9(5) (2020-05-07)
Sprouts and microgreens are a rich source of various bioactive compounds. Seeds of lentil, fenugreek, alfalfa, and daikon radish seeds were germinated and the contents of the polyamines agmatine (AGM), putrescine (PUT), cadaverine (CAD), spermidine (SPD), and spermine (SPM) in
Journal of chromatography, 614(1), 153-158 (1993-04-21)
A rapid reversed-phase high-performance liquid chromatographic method, using pre-column derivatization with benzoyl chloride and ultraviolet detection at 254 nm, was developed for the simultaneous measurement of polyamines and their monoacetyl derivatives. Calibration curves were linear for concentrations from 1.25 to
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